Western Blot (WB)
(Western blot analysis of Beclin 1 expression in Jurkat (Lane 1,2) and mouse intestine (Lane 3) lysates.)
Rabbit Beclin 1 Polyclonal Antibody | anti-BECN1 antibody
Beclin 1 Antibody
Gene Names
BECN1; ATG6; VPS30; beclin1
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
Beclin 1; Polyclonal Antibody; Beclin 1 Antibody; Rabbit Polyclonal Beclin 1 Antibody; Polyclonal Beclin 1 antibody; anti-Beclin 1 antibody; Beclin-1 antibody; ATG6 antibody; Beclin 1 antibody; BECN1 antibody; Beclin -1 antibody; Beclin -1; beclin1 antibody; GT197 antibody; VPS30 antibody; anti-BECN1 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer containing 1% BSA, 50% Glycerol, and 0.02% Thimerosal
Concentration
200 ug/ml (varies by lot)
Sequence Length
450
Applicable Applications for anti-BECN1 antibody
Western Blot (WB)
Application Notes
WB: 0.5-2 ug/ml
Immunogen
Beclin 1 antibody was raised in Rabbit using synthetic peptide corresponding to residues around amino acid 25 of mouse Beclin 1 as the immunogen.
Cross-Reactivity
Human, Mouse
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Beclin 1 expression in Jurkat (Lane 1,2) and mouse intestine (Lane 3) lysates.)
Western Blot (WB)
(Western blot analysis of Beclin 1 expression in Jurkat (Lane 1,2) and mouse intestine (Lane 3) lysates.)
Related Product Information for anti-BECN1 antibody
Beclin is a Bcl-2 binding protein. Its structure includes a Bcl-2 binding coiled-coil region, and a leucine-rich nuclear export signal. Beclin protein colocalizes with intracytoplasmic organelles and nuclei in normal COS7 and MCF7 cells. Beclin interaction with Bcl-2 may be involved with host viral defense, since over expression of beclin inhibits Sindbis virus replication and expression of beclin lacking the Bcl-2 binding domain has no antiviral effects.
Product Categories/Family for anti-BECN1 antibody
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Research Articles on BECN1
Similar Products
Product Notes
The BECN1 (Catalog #AAA5311413) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Beclin 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-2 ug/ml. Researchers should empirically determine the suitability of the BECN1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Beclin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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