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Western Blot (WB) (Western blot analysis of BCL3 in 293 cell lysate with BCL3 antibody at 1 μg/mL.)

Rabbit anti-Human BCL3 Polyclonal Antibody | anti-BCL3 antibody

BCL3 Antibody

Gene Names
BCL3; BCL4; D19S37
Reactivity
Human
Applications
ELISA, Western Blot
Purity
BCL3 Antibody is affinity chromatography purified via peptide column.
Synonyms
BCL3; Polyclonal Antibody; BCL3 Antibody; BCL4; D19S37; B-cell lymphoma 3 protein; Proto-oncogene BCL3; BCL-3; B-cell CLL/lymphoma 3; anti-BCL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
BCL3 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
454
Applicable Applications for anti-BCL3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 mug/mL.
Conjugate
Unconjugated
Immunogen
Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3.
Buffer
BCL3 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
BCL3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

Western Blot (WB)

(Western blot analysis of BCL3 in 293 cell lysate with BCL3 antibody at 1 μg/mL.)

Western Blot (WB) (Western blot analysis of BCL3 in 293 cell lysate with BCL3 antibody at 1 μg/mL.)
Related Product Information for anti-BCL3 antibody
BCL3 Antibody: The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-κ-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-κ-B proteins. The expression of this gene can be induced by NF-κ-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-κ-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
602
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 50 kDa
NCBI Official Full Name
B-cell lymphoma 3 protein
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 3
NCBI Official Symbol
BCL3
NCBI Official Synonym Symbols
BCL4; D19S37
NCBI Protein Information
B-cell lymphoma 3 protein; BCL-3; proto-oncogene BCL3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3-encoded protein; chronic lymphatic leukemia protein
UniProt Protein Name
B-cell lymphoma 3 protein
Protein Family
UniProt Gene Name
BCL3
UniProt Synonym Gene Names
BCL4; D19S37; BCL-3
UniProt Entry Name
BCL3_HUMAN

NCBI Description

This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]

Uniprot Description

Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation ().

Research Articles on BCL3

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Product Notes

The BCL3 bcl3 (Catalog #AAA153686) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCL3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BCL3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the BCL3 bcl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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