Rabbit anti-Human PAX7 Polyclonal Antibody | anti-PAX7 antibody

PAX7, ID (PAX7, HUP1, Paired box protein Pax-7, HuP1) (MaxLight 750)

Cat. Num. AAA6331207

• Gene Names: PAX7; HUP1; RMS2; PAX7B
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: PAX7; Polyclonal Antibody; ID (PAX7; HUP1; Paired box protein Pax-7; HuP1) (MaxLight 750); HuP1; anti-PAX7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human PAX7.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

• Applicable Applications for anti-PAX7 antibody: Immunohistochemistry (IHC) Paraffin, Western Blot (WB), FLISA
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 181-210 in the central region of human PAX7, UniProt Accession #P23759. Species sequence homology: mouse
• Conjugate: MaxLight750
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of MBS643015 in CEM cell line lysates (35ug/lane).This demonstrates that MBS643015 detected the PAX7 protein (arrow).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of formalin fixed and paraffin embedded human stomach tissue using MBS643015 followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MBS643015 for immunohistochemistry.)

Product Categories/Family for anti-PAX7 antibody

Antibodies; Transcription Factors

References

1. Shimada, M., et al. Hum. Genet. 128(4):433-441 (2010). 2. Williamson, D., et al. J. Clin. Oncol. 28(13):2151-2158 (2010). 3. Xynos, A., et al. Stem Cells 28(5):965-973 (2010). 4. Edwards, T.L., et al. Ann. Hum. Genet. 74(2):97-109 (2010). 5. Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 207029223
• NCBI GeneID: 5081
• NCBI Accession #: NP_001128726.1; NP_039236.1
• NCBI GenBank Nucleotide #: NM_001135254.1
• UniProt Accession #: P23759; Q0VA99; Q2PJS5; E9PFV9
• Molecular Weight: 55119 MW
• NCBI Official Full Name: paired box protein Pax-7 isoform 3
• NCBI Official Synonym Full Names: paired box 7
• NCBI Official Symbol: PAX7
• NCBI Official Synonym Symbols: HUP1; RMS2; PAX7B
• NCBI Protein Information: paired box protein Pax-7
• UniProt Protein Name: Paired box protein Pax-7
• Protein Family: Paired box protein
• UniProt Gene Name: PAX7
• UniProt Synonym Gene Names: HUP1

NCBI Description

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Uniprot Description

Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation.