Western Blot (WB)
(Western blot analysis of BATF2 using HeLa whole cell lysates)
Rabbit anti-Human BATF2 Polyclonal Antibody | anti-BATF2 antibody
BATF2 Antibody
Gene Names
BATF2; SARI
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
BATF2; Polyclonal Antibody; BATF2 Antibody; B ATF 2; Basic leucine zipper transcriptional factor ATF like 2; MGC20410; SARI; Suppressor of AP 1 regulated by IFN; anti-BATF2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
BATF2 antibody detects endogenous levels of total BATF2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
250
Applicable Applications for anti-BATF2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human BATF2
Subcellular Location
Nucleus
Tissue Specificity
By type I interferon. Down-regulated in most hepatocellular carcinoma tumorous tissues (at protein level).
Predicted Cross Reactivity
Pig, Horse, Sheep, Dog
Similarity
Pig (91%), Horse (82%), Sheep (91%), Dog (90%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of BATF2 using HeLa whole cell lysates)
Western Blot (WB)
(Western blot analysis of BATF2 using HeLa whole cell lysates)
Related Product Information for anti-BATF2 antibody
Function: AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8+ thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
Subunit Structure: Heterodimer; heterodimerizes with JUN family proteins.
Similarity: Belongs to the bZIP family.
Subunit Structure: Heterodimer; heterodimerizes with JUN family proteins.
Similarity: Belongs to the bZIP family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 29 kDa
Predicted: 30 kDa
Predicted: 30 kDa
NCBI Official Full Name
basic leucine zipper transcriptional factor ATF-like 2 isoform 2
NCBI Official Synonym Full Names
basic leucine zipper ATF-like transcription factor 2
NCBI Official Symbol
BATF2
NCBI Official Synonym Symbols
SARI
NCBI Protein Information
basic leucine zipper transcriptional factor ATF-like 2
UniProt Protein Name
Basic leucine zipper transcriptional factor ATF-like 2
Protein Family
UniProt Gene Name
BATF2
UniProt Synonym Gene Names
B-ATF-2; SARI
Uniprot Description
AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8+ thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
Research Articles on BATF2
Similar Products
Product Notes
The BATF2 batf2 (Catalog #AAA9609583) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BATF2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BATF2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the BATF2 batf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BATF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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