Rabbit BAG5 Polyclonal Antibody | anti-BAG5 antibody

BAG5 Antibody (Rabbit Polyclonal)

Gene Names

BAG5; BAG-5

Reactivity

Human
Predicted: Rat, Mouse

Applications

ELISA, Western Blot, Immunohistochemistry

Synonyms

BAG5; Polyclonal Antibody; BAG5 Antibody (Rabbit Polyclonal); anti-BAG5 antibody

Ordering
Cat. Num. AAA8508303 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Host

Rabbit

Reactivity

Human
Predicted: Rat, Mouse

Clonality

Polyclonal

Form/Format

Purified by protein affinity column containing 1% BSA and 0.02% NaN3

Sequence Length

1859

Applicable Applications for anti-BAG5 antibody

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes

ELISA: 1:20,000-1:80,000
WB: 1:200-1:1,000
IHC: 1:100-1:500

Preparation and Storage

Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Related Product Information for anti-BAG5 antibody

Rabbit polyclonal BAG5(1) antibody was raised against a recombinate human BAG5 protein 237-447aa (BC050551).

NCBI and Uniprot Product Information

NCBI GI #

29792007

NCBI GeneID

9529

Molecular Weight

56,027 Da

NCBI Official Full Name

Homo sapiens BCL2-associated athanogene 5, mRNA

NCBI Official Synonym Full Names

BCL2 associated athanogene 5

NCBI Official Symbol

BAG5

NCBI Official Synonym Symbols

BAG-5

NCBI Protein Information

BAG family molecular chaperone regulator 5

UniProt Protein Name

BAG family molecular chaperone regulator 5

Protein Family

BAG family molecular chaperone regulator

UniProt Gene Name

BAG5

UniProt Synonym Gene Names

KIAA0873; BAG-5

NCBI Description

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN (). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.

Research Articles on BAG5

1. Subsequent BAG5 upregulation ameliorated the tumor-suppressive effects of miR-127-3p overexpression in epithelial ovarian cancer (EOC). In conclusion, miR-127-3p functions as a tumor suppressor in EOC, and its influence on EOC is directly through regulation of BAG5.

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Product Notes

The BAG5 bag5 (Catalog #AAA8508303) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BAG5 Antibody (Rabbit Polyclonal) reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's BAG5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:200-1:1,000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the BAG5 bag5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BAG5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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