Western Blot (WB)
(Anti- CD79A picoband antibody, MBS177454, Western blottingAll lanes: Anti CD79a (MBS177454) at 0.5ug/mlWB: Recombinant human CD79a Protein 0.5ngPredicted bind size: 45KDObserved bind size: 45KD)
Rabbit B-cell antigen receptor complex-associated protein alpha chain Polyclonal Antibody | anti-CD79A antibody
Anti-CD79a Antibody
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunohistochemistry (Paraffin-embedded Section): Concentration: 0.5-1mug/ml; Tested Species: Human
Immunohistochemistry (Frozen Section): Concentration: 0.5-1mug/ml; Tested Species: Human
Western Blot (WB)
(Anti- CD79A picoband antibody, MBS177454, Western blottingAll lanes: Anti CD79a (MBS177454) at 0.5ug/mlWB: Recombinant human CD79a Protein 0.5ngPredicted bind size: 45KDObserved bind size: 45KD)
Western Blot (WB)
(Anti- CD79A picoband antibody, MBS177454, Western blottingAll lanes: Anti CD79a (MBS177454) at 0.5ug/mlWB: Recombinant human CD79a Protein 0.5ngPredicted bind size: 45KDObserved bind size: 45KD)
Western Blot (WB)
(Anti- CD79A picoband antibody, MBS177454, Western blottingAll lanes: Anti CD79a (MBS177454) at 0.5ug/mlLane 1: Human Placenta Tissue Lysate at 50ugLane 2: Rat Spleen Tissue Lysate at 50ugPredicted bind size: 25KDObserved bind size: 37KD)
Western Blot (WB)
(Anti- CD79A picoband antibody, MBS177454, Western blottingAll lanes: Anti CD79a (MBS177454) at 0.5ug/mlLane 1: Human Placenta Tissue Lysate at 50ugLane 2: Rat Spleen Tissue Lysate at 50ugPredicted bind size: 25KDObserved bind size: 37KD)
Immunohistochemistry (IHC)
(Anti- CD79A picoband antibody, MBS177454, IHC(P)IHC(P): Human Tonsil Tissue )
Immunohistochemistry (IHC)
(Anti- CD79A picoband antibody, MBS177454, IHC(P)IHC(P): Human Tonsil Tissue )
Background: Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene. It is mapped to 19q13.2. CD79A is a membrane protein with an extracellular immunoglobulin domain, a single span transmembrane region and a short cytoplasmic domain. Genetic deletion of the transmembrane exon of CD79A results in loss of CD79A protein and a complete block of B cell development at the pro to pre B cell transition. Similarly, humans with homozygous splice variants in CD79A predicted to result in loss of the transmembrane region and a truncated or absent protein display agammaglobulinemia and no peripheral B cells.
NCBI and Uniprot Product Information
NCBI Description
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described.
Protein type: Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: multivesicular body; plasma membrane; integral to membrane; B cell receptor complex; lipid raft; external side of plasma membrane
Molecular Function: transmembrane receptor activity
Biological Process: B cell proliferation; B cell receptor signaling pathway; B cell activation; B cell differentiation
Disease: Agammaglobulinemia 3, Autosomal Recessive
Research Articles on CD79A
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Product Notes
The CD79A cd79a (Catalog #AAA177454) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD79a Antibody reacts with Human, Rat. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's B-cell antigen receptor complex-associated protein alpha chain can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry (ICC). Western Blot: Concentration: 0.1-0.5mug/ml; Tested Species: Human, Rat Immunohistochemistry (Paraffin-embedded Section): Concentration: 0.5-1mug/ml; Tested Species: Human Immunohistochemistry (Frozen Section): Concentration: 0.5-1mug/ml; Tested Species: Human. Researchers should empirically determine the suitability of the CD79A cd79a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "B-cell antigen receptor complex-associated protein alpha chain, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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