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Immunohistochemistry (IHC) (IH analyisis of Alzheimer’s disease brain showing staining of vessels containing amyloid beta deposits at 1:200 dilution of MBS613286 in formalin-fixed, paraffin-embedded, formic-acid treated section of hippocampus.)

Rabbit anti-Human b-Amyloid Polyclonal Antibody

b-Amyloid, NT

Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Serum
Processed whole rabbit serum.
Synonyms
b-Amyloid; Polyclonal Antibody; NT; Anti -b-Amyloid; anti-b-Amyloid antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes Amyloid b peptide. Species Reactivity: Human. Will discriminate amyloid b from other CNS amyloids.
Purity/Purification
Serum
Processed whole rabbit serum.
Form/Format
Supplied as a liquid in 0.1% sodium azide.
Applicable Applications for anti-b-Amyloid antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA and Immunohistochemistry (formalin fixed and paraffin embedded sections).
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:200
Immunogen
A synthetic peptide corresponding to aa sequence 1-14 (1DAEFRHDSGYEVHH14) of the human amyloid b protein.
Positive Control
Alzheimer's disease brain.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Immunohistochemistry (IHC)

(IH analyisis of Alzheimer’s disease brain showing staining of vessels containing amyloid beta deposits at 1:200 dilution of MBS613286 in formalin-fixed, paraffin-embedded, formic-acid treated section of hippocampus.)

Immunohistochemistry (IHC) (IH analyisis of Alzheimer’s disease brain showing staining of vessels containing amyloid beta deposits at 1:200 dilution of MBS613286 in formalin-fixed, paraffin-embedded, formic-acid treated section of hippocampus.)

Immunohistochemistry (IHC)

(IH analyisis of Alzheimer’s disease brain showing staining of amyloid cores in senile plaques at 1:200 dilution of MBS613286 in formalin-fixed, paraffin-embedded, formic-acid treated section of hippocampus.)

Immunohistochemistry (IHC) (IH analyisis of Alzheimer’s disease brain showing staining of amyloid cores in senile plaques at 1:200 dilution of MBS613286 in formalin-fixed, paraffin-embedded, formic-acid treated section of hippocampus.)
Related Product Information for anti-b-Amyloid antibody
Amyloid b (Ab) accumulates in the senile plaques of the brain during Alzheimer's disease and during certain classes of cerebrovascular angiopathy. Ab generation is initiated by proteolytic cleavage of the Amyloid Precursor Protein (APP) by b-secretase (BACE) at a site which corresponds to the Ab N terminus. A second proteolytic cleavage by g-secretase at a site corresponding to the Ab C terminus releases the Ab peptide. The insoluble Ab peptide forms aggregates in the vessels and senile plaques of Alzheimer's disease brains.
Product Categories/Family for anti-b-Amyloid antibody

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Product Notes

The b-Amyloid (Catalog #AAA613286) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The b-Amyloid, NT reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's b-Amyloid can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC). Suitable for use in ELISA and Immunohistochemistry (formalin fixed and paraffin embedded sections). Dilution: ELISA: 1:1,000 Immunohistochemistry: 1:200. Researchers should empirically determine the suitability of the b-Amyloid for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "b-Amyloid, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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