Immunohistochemistry (IHC)
(Anti-AVPR1A antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit AVPR1A / V1a Receptor Polyclonal Antibody | anti-AVPR1A antibody
Rabbit Polyclonal to Human AVPR1A / V1a Receptor
Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity)
Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity)
Immunohistochemistry (IHC)
(Anti-AVPR1A antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-AVPR1A antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]
Uniprot Description
AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR
Chromosomal Location of Human Ortholog: 12q14-q15
Cellular Component: integral to plasma membrane; plasma membrane; cytoplasmic vesicle; endosome
Molecular Function: protein binding; protein kinase C binding; peptide hormone binding; V1A vasopressin receptor binding; peptide binding; vasopressin receptor activity
Biological Process: blood circulation; positive regulation of cellular pH reduction; positive regulation of glutamate secretion; cellular response to water deprivation; positive regulation of systemic arterial blood pressure; elevation of cytosolic calcium ion concentration; positive regulation of cell proliferation; response to corticosterone stimulus; positive regulation of prostaglandin biosynthetic process; penile erection; grooming behavior; generation of precursor metabolites and energy; maternal behavior; calcium-mediated signaling; myotube differentiation; positive regulation of heart rate; social behavior; positive regulation of cell growth; cellular response to hormone stimulus; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; negative regulation of transmission of nerve impulse; phospholipase C activation; positive regulation of vasoconstriction; sperm ejaculation
Research Articles on AVPR1A
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Product Notes
The AVPR1A avpr1a (Catalog #AAA243288) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human AVPR1A / V1a Receptor reacts with Human Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's AVPR1A / V1a Receptor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (2.5 ug/ml). Researchers should empirically determine the suitability of the AVPR1A avpr1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AVPR1A / V1a Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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