Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Human testis tissue Amount of lysate: 40ug per lane Primary antibody: 1/600 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Rabbit anti-Human AURKAIP1 Polyclonal Antibody | anti-AURKAIP1 antibody
AURKAIP1 Antibody
Gene Names
AURKAIP1; AIP; AKIP; MRP-S38
Reactivity
Human
Applications
Western Blot
Purity
Antigen affinity purification.
Synonyms
AURKAIP1; Polyclonal Antibody; AURKAIP1 Antibody; AIP; AKIP; MRP-S38; anti-AURKAIP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total AURKAIP1 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
2.6 mg/ml (varies by lot)
Sequence Length
199
Applicable Applications for anti-AURKAIP1 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500-1:2000
Immunogen Type
Recombinant Protein
Immunogen Description
Full length fusion protein
Target Name
AURKAIP1
Preparation and Storage
Store at -20 degree C
Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Human testis tissue Amount of lysate: 40ug per lane Primary antibody: 1/600 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Human testis tissue Amount of lysate: 40ug per lane Primary antibody: 1/600 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Related Product Information for anti-AURKAIP1 antibody
AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Product Categories/Family for anti-AURKAIP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,354 Da
NCBI Official Full Name
aurora kinase A-interacting protein
NCBI Official Synonym Full Names
aurora kinase A interacting protein 1
NCBI Official Symbol
AURKAIP1
NCBI Official Synonym Symbols
AIP; AKIP; MRP-S38
NCBI Protein Information
aurora kinase A-interacting protein
UniProt Protein Name
Aurora kinase A-interacting protein
Protein Family
UniProt Gene Name
AURKAIP1
UniProt Synonym Gene Names
AIP; AKIP; MRPS38; AURKA-interacting protein; MRP-S38
UniProt Entry Name
AKIP_HUMAN
Uniprot Description
AKIP: May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: nucleoplasm; mitochondrion; intracellular membrane-bound organelle; mitochondrial inner membrane; nucleus
Molecular Function: protein binding
Biological Process: mitochondrial translation; positive regulation of proteolysis; organelle organization and biogenesis; negative regulation of mitosis
Research Articles on AURKAIP1
Similar Products
Product Notes
The AURKAIP1 aurkaip1 (Catalog #AAA9410384) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AURKAIP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AURKAIP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500-1:2000. Researchers should empirically determine the suitability of the AURKAIP1 aurkaip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AURKAIP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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