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Western Blot (WB) (ATPGD1 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the ATPGD1 antibody detected the ATPGD1 protein (arrow).)

Rabbit anti-Human, Mouse ATPGD1 Polyclonal Antibody | anti-CARNS1 antibody

ATPGD1, NT (CARNS1, ATPGD1, KIAA1394, Carnosine synthase 1, ATP-grasp domain-containing protein 1)

Gene Names
CARNS1; ATPGD1
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
ATPGD1; Polyclonal Antibody; NT (CARNS1; KIAA1394; Carnosine synthase 1; ATP-grasp domain-containing protein 1); Anti -ATPGD1; anti-CARNS1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Human, mouse
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-CARNS1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Immunogen
ATPGD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-276 amino acids from the N-terminal region of human ATPGD1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ATPGD1 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the ATPGD1 antibody detected the ATPGD1 protein (arrow).)

Western Blot (WB) (ATPGD1 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the ATPGD1 antibody detected the ATPGD1 protein (arrow).)

Immunohistochemistry (IHC)

(ATPGD1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ATPGD1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (ATPGD1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ATPGD1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-CARNS1 antibody
CARNS1 (EC 6.3.2.11), a member of the ATP-grasp family of ATPases, catalyzes the formation of carnosine (beta-alanyl-L-histidine) and homocarnosine (gamma-aminobutyryl-L-histidine), which are found mainly in skeletal muscle and the central nervous system, respectively (Drozak et al., 2010 [PubMed 20097752]).
Product Categories/Family for anti-CARNS1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
88,484 Da
NCBI Official Full Name
ATPGD1 protein
NCBI Official Synonym Full Names
carnosine synthase 1
NCBI Official Symbol
CARNS1
NCBI Official Synonym Symbols
ATPGD1
NCBI Protein Information
carnosine synthase 1; ATP-grasp domain containing 1; ATP-grasp domain-containing protein 1
UniProt Protein Name
Carnosine synthase 1
Protein Family
UniProt Gene Name
CARNS1
UniProt Synonym Gene Names
ATPGD1; KIAA1394
UniProt Entry Name
CRNS1_HUMAN

NCBI Description

CARNS1 (EC 6.3.2.11), a member of the ATP-grasp family of ATPases, catalyzes the formation of carnosine (beta-alanyl-L-histidine) and homocarnosine (gamma-aminobutyryl-L-histidine), which are found mainly in skeletal muscle and the central nervous system, respectively (Drozak et al., 2010 [PubMed 20097752]).[supplied by OMIM, Apr 2010]

Uniprot Description

ATPGD1: Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.11

Chromosomal Location of Human Ortholog: 11q13.2

Molecular Function: carnosine synthase activity; metal ion binding; ATPase activity; ATP binding

Research Articles on CARNS1

Similar Products

Product Notes

The CARNS1 carns1 (Catalog #AAA6000413) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATPGD1, NT (CARNS1, ATPGD1, KIAA1394, Carnosine synthase 1, ATP-grasp domain-containing protein 1) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ATPGD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100. Researchers should empirically determine the suitability of the CARNS1 carns1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATPGD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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