Western Blot (WB)
(WB Suggested Anti-ATP11B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Liver)
Rabbit ATP11B Polyclonal Antibody | anti-ATP11B antibody
ATP11B antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-ATP11B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Liver)
Western Blot (WB)
(WB Suggested Anti-ATP11B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Liver)
Target Description: P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-91 BI861412.1 1-91 92-104 AF156548.1 1-13 105-809 BC042180.1 105-809 810-1001 AF156548.1 719-910 1002-1244 BX489704.1 417-659 1245-1346 BF372979.1 79-180 1347-1791 BU431705.1 43-487 1792-4720 AB023173.1 22-2950 4721-6422 AL133061.1 2205-3906 6423-7314 AB023173.1 4651-5542 7315-7368 AL133061.1 4799-4852
NCBI and Uniprot Product Information
NCBI Description
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]
Uniprot Description
ATP11B: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. Interacts with TMEM30A
Protein type: Hydrolase; Transporter, ion channel; Membrane protein, multi-pass; Membrane protein, integral; Transporter; EC 3.6.3.1
Chromosomal Location of Human Ortholog: 3q27
Cellular Component: Golgi apparatus; recycling endosome; membrane; recycling endosome membrane; endoplasmic reticulum; early endosome; integral to membrane; plasma membrane; nuclear inner membrane
Molecular Function: phospholipid-translocating ATPase activity; protein binding; ion transmembrane transporter activity; magnesium ion binding; ATP binding
Biological Process: phospholipid translocation; metabolic process; aminophospholipid transport; ion transport; transmembrane transport
Research Articles on ATP11B
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Product Notes
The ATP11B atp11b (Catalog #AAA3208418) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATP11B antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's ATP11B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the ATP11B atp11b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: DIVRIAKDEI FPADLVLLSS DRLDGSCHVT TASLDGETNL KTHVAVPETA. It is sometimes possible for the material contained within the vial of "ATP11B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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