Western Blot (WB)
(Western blot analysis of APG16L1 in Jurkat cell lysates (Lane 1 & 2).)
Rabbit ATG16 Polyclonal Antibody | anti-ATG16 antibody
ATG16 Antibody
Gene Names
atg16l1; atg16; atg16l
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
ATG16; Polyclonal Antibody; ATG16 Antibody; Rabbit Polyclonal ATG16 Antibody; Polyclonal ATG16 antibody; anti-ATG16 antibody; ATG-16 antibody; ATG-16; ATG 16 antibody; ATG 16; APG16 antibody; APTG 16 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer containing 30% Glycerol, 0.5 mg/ml BSA and 0.01% Thimerosal
Concentration
500 ug/ml (varies by lot)
Sequence Length
622
Applicable Applications for anti-ATG16 antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Immunogen
ATG16 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 565 of human APG16 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of APG16L1 in Jurkat cell lysates (Lane 1 & 2).)
Western Blot (WB)
(Western blot analysis of APG16L1 in Jurkat cell lysates (Lane 1 & 2).)
Related Product Information for anti-ATG16 antibody
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR through phosphorylation of autophagy protein APG1. ATG16, another member of the autophagy protein family, forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome. Because mammalian ATG16 has seven WD-repeats in its C-terminal domain, it has been suggested that these may form a platform for further protein-protein interactions. Multiple isoforms of ATG16 are known to exist.
Product Categories/Family for anti-ATG16 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
autophagy-related protein 16
NCBI Official Synonym Full Names
autophagy related 16 like 1
NCBI Official Symbol
atg16l1
NCBI Official Synonym Symbols
atg16; atg16l
NCBI Protein Information
autophagy-related protein 16
UniProt Protein Name
Autophagy-related protein 16
Protein Family
UniProt Gene Name
atg16
UniProt Synonym Gene Names
apg16l
Uniprot Description
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
Similar Products
Product Notes
The ATG16 atg16 (Catalog #AAA5311540) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ATG16 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the ATG16 atg16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATG16, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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