Mouse anti-Human ASB9 Polyclonal Antibody | anti-ASB9 antibody

ASB9 (Ankyrin Repeat and SOCS Box Protein 9, ASB-9, DKFZp564L0862, FLJ20636, MGC4954)

Cat. Num. AAA6000291

• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: ASB9; Polyclonal Antibody; ASB9 (Ankyrin Repeat and SOCS Box Protein 9; ASB-9; DKFZp564L0862; FLJ20636; MGC4954); Anti -ASB9 (Ankyrin Repeat and SOCS Box Protein 9; anti-ASB9 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ASB9.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MDGKQGGMDGSKPAGPRDFPGIRLLSNPLMGDAVSDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELVPPESPLAQLFLEREGPPSLMQLCRLRIRKCFGIQQHHKITKLVLPEDLKQFLLHL

• Applicable Applications for anti-ASB9 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human ASB9, aa1-294 (NP_001026909.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ASB9 polyclonal antibody. Western Blot analysis of ASB9 expression in human liver.)

Western Blot (WB)

(Western Blot analysis of ASB9 expression in transfected 293T cell line by ASB9 polyclonal antibody. Lane 1: ASB9 transfected lysate (32.34kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-ASB9 antibody

Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A.

Product Categories/Family for anti-ASB9 antibody

Antibodies; Abs to SOCS

NCBI and Uniprot Product Information

• NCBI GI #: 72534772
• NCBI GeneID: 140462
• NCBI Accession #: NP_001026909.1
• NCBI GenBank Nucleotide #: NM_001031739.2
• UniProt Accession #: Q96DX5; Q9BVF5; Q9NWS5; Q9Y4T3; A8K8A5
• Molecular Weight: 31,858 Da
• NCBI Official Full Name: ankyrin repeat and SOCS box protein 9 isoform 1
• NCBI Official Synonym Full Names: ankyrin repeat and SOCS box containing 9
• NCBI Official Symbol: ASB9
• NCBI Protein Information: ankyrin repeat and SOCS box protein 9; ASB-9; ankyrin repeat and SOCS box-containing 9; ankyrin repeat and suppressor of cytokine signaling box protein 9
• UniProt Protein Name: Ankyrin repeat and SOCS box protein 9
• Protein Family: Ankyrin repeat and SOCS box protein
• UniProt Gene Name: ASB9
• UniProt Synonym Gene Names: ASB-9
• UniProt Entry Name: ASB9_HUMAN

NCBI Description

This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Uniprot Description

ASB9: Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: Xp22.2

Cellular Component: mitochondrion

Molecular Function: protein binding

Biological Process: positive regulation of protein catabolic process; protein ubiquitination