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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human stomach using ARPC1A Polyclonal Antibody at dilution of 1:100 (40x lens).)

Rabbit ARPC1A Polyclonal Antibody | anti-ARPC1A antibody

ARPC1A Polyclonal Antibody

Gene Names
ARPC1A; Arc40; SOP2L; HEL-68; SOP2Hs
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
Affinity purification
Synonyms
ARPC1A; Polyclonal Antibody; ARPC1A Polyclonal Antibody; Arc40; HEL-68; HEL-S-307; SOP2Hs; SOP2L; anti-ARPC1A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-ARPC1A antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Recombinant fusion protein of human ARPC1A (NP_0064002)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human stomach using ARPC1A Polyclonal Antibody at dilution of 1:100 (40x lens).)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human stomach using ARPC1A Polyclonal Antibody at dilution of 1:100 (40x lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human uterine cancer using ARPC1A Polyclonal Antibody at dilution of 1:100 (40x lens).)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human uterine cancer using ARPC1A Polyclonal Antibody at dilution of 1:100 (40x lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Mouse kidney using ARPC1A Polyclonal Antibody at dilution of 1:100 (40x lens).)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse kidney using ARPC1A Polyclonal Antibody at dilution of 1:100 (40x lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Mouse heart using ARPC1A Polyclonal Antibody at dilution of 1:100 (40x lens).)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse heart using ARPC1A Polyclonal Antibody at dilution of 1:100 (40x lens).)
Related Product Information for anti-ARPC1A antibody
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-ARPC1A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
370
NCBI Official Full Name
Actin-related protein 2/3 complex subunit 1A
NCBI Official Synonym Full Names
actin related protein 2/3 complex, subunit 1A, 41kDa
NCBI Official Symbol
ARPC1A
NCBI Official Synonym Symbols
Arc40; SOP2L; HEL-68; SOP2Hs
NCBI Protein Information
actin-related protein 2/3 complex subunit 1A; SOP2-like protein; epididymis luminal protein 68; actin binding protein (Schizosaccharomyces pombe sop2-like)
UniProt Protein Name
Actin-related protein 2/3 complex subunit 1A
UniProt Gene Name
ARPC1A
UniProt Synonym Gene Names
SOP2L
UniProt Entry Name
ARC1A_HUMAN

NCBI Description

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Uniprot Description

ARPC1A: Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Belongs to the WD repeat ARPC1 family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: Arp2/3 protein complex; cytosol; actin cytoskeleton

Molecular Function: actin filament binding; actin binding

Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; actin cytoskeleton organization and biogenesis

Research Articles on ARPC1A

Similar Products

Product Notes

The ARPC1A arpc1a (Catalog #AAA2565875) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARPC1A Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ARPC1A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the ARPC1A arpc1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARPC1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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