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Rabbit Aromatase Polyclonal Antibody | anti-ARO antibody

Aromatase Antibody BIOTIN

Gene Names
CYP19A1; ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
Immobilized antigen affinity chromatography
Synonyms
Aromatase; Polyclonal Antibody; Aromatase Antibody BIOTIN; BIOTIN-Conjugated Aromatase Antibody; ARO antibody; ARO1 antibody; Aromatase antibody; CP19A_HUMAN antibody; CPV1 antibody; CYAR antibody; Cyp19a1 antibody; CYPXIX antibody; Cytochrome P-450AROM antibody; Cytochrome P450; family 19; subfamily A; polypeptide 1 antibody; subfamily XIX (aromatization of androgens) antibody; Estrogen synthase antibody; Flavoprotein linked monooxygenase antibody; Microsomal monooxygena; 450AROM antibody; anti-ARO antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immobilized antigen affinity chromatography
Concentration
0.5 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
503
Applicable Applications for anti-ARO antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:50,000
IP: 1:200
WB: 1:2,500-1:5,000
Immunogen
Synthetic peptide taken within amino acid region 400-450 on human Aromatase protein.
Conjugation
BIOTIN
Molecular Function
aromatase activity; electron carrier activity; heme binding; iron ion binding
Subcellular Location
Membrane; Peripheral membrane protein
Preparation and Storage
Store at -20 degree C for long term storage.
Related Product Information for anti-ARO antibody
Overview: Catalyzes the formation of aromatic C18 estrogens from C19 androgens.

Structure: Belongs to the cytochrome P450 family.

Expression: Widely expressed, including in adult and fetal brain, placenta, skin fibroblasts, adipose tissue and gonads.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,518 Da
NCBI Official Full Name
aromatase
NCBI Official Synonym Full Names
cytochrome P450 family 19 subfamily A member 1
NCBI Official Symbol
CYP19A1
NCBI Official Synonym Symbols
ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
NCBI Protein Information
aromatase
UniProt Protein Name
Aromatase
Protein Family
UniProt Gene Name
CYP19A1
UniProt Synonym Gene Names
ARO1; CYAR; CYP19

NCBI Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]

Uniprot Description

Catalyzes the formation of aromatic C18 estrogens from C19 androgens.

Research Articles on ARO

Similar Products

Product Notes

The ARO cyp19a1 (Catalog #AAA5400331) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Aromatase Antibody BIOTIN reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Aromatase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:50,000 IP: 1:200 WB: 1:2,500-1:5,000. Researchers should empirically determine the suitability of the ARO cyp19a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Aromatase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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