Western Blot (WB)
(Western Blot: Sample: Human HepG2 cell lysate; Primary Ab: 3ug/ml Rabbit Anti-Rat AR Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Rat Androgen Receptor (AR) Polyclonal Antibody | anti-AR antibody
Polyclonal Antibody to Androgen Receptor (AR)
MGHHHHHHSGSEF- VNRVPYPSPS CVKSEMGPWM ENYSGPYGDM RLDSTRDHVL PIDYYFPPQK TCLICGDEAS GCHYGALTCG SCKVFFKRAA EGKQKYLCAS RNDCTIDKFR RKNCPSCRLR KCYEAGMTLG ARKLKKLGNL KLQEEGENSS AGSPTEDPSQ KMTVSHIEGY ECQPIFLNVL EAIEPGVVCA GHDNNQPDS
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Human HepG2 cell lysate; Primary Ab: 3ug/ml Rabbit Anti-Rat AR Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Human HepG2 cell lysate; Primary Ab: 3ug/ml Rabbit Anti-Rat AR Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Rat Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Rat Tissue))
NCBI and Uniprot Product Information
NCBI Description
binds androgens and activates transcription; required for male sexual development [RGD, Feb 2006]
Uniprot Description
AR: a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described.
Protein type: DNA-binding; Nuclear receptor; Transcription factor
Chromosomal Location of Human Ortholog: Xq22
Cellular Component: axon; cytoplasm; dendrite; nuclear chromatin; nuclear speck; nucleus; plasma membrane; protein complex
Molecular Function: androgen binding; androgen receptor activity; androgen receptor binding; ATPase binding; beta-catenin binding; chromatin binding; DNA binding; DNA binding transcription factor activity; enzyme binding; ligand-dependent nuclear receptor activity; protein binding; protein domain specific binding; receptor binding; ribonucleotide binding; sequence-specific DNA binding; steroid binding; transcription factor binding; zinc ion binding
Biological Process: androgen receptor signaling pathway; animal organ formation; cellular process; copulation; fertilization; in utero embryonic development; intracellular receptor signaling pathway; Leydig cell differentiation; male courtship behavior; male genitalia morphogenesis; male gonad development; male sex differentiation; male somatic sex determination; multicellular organism growth; negative regulation of cell proliferation; negative regulation of epithelial cell proliferation; negative regulation of integrin biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of integrin biosynthetic process; positive regulation of intracellular estrogen receptor signaling pathway; positive regulation of MAPK cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase III promoter; positive regulation of transcription, DNA-templated; protein oligomerization; regulation of catalytic activity; regulation of developmental growth; regulation of gene expression; regulation of systemic arterial blood pressure; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-templated; reproductive behavior; reproductive structure development; response to estradiol; response to insulin stimulus; response to testosterone stimulus; single fertilization; skeletal muscle hypertrophy; spermatogenesis; transcription from RNA polymerase II promoter; transcription, DNA-dependent
Research Articles on AR
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Product Notes
The AR ar (Catalog #AAA2004562) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Androgen Receptor (AR) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Androgen Receptor (AR) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the AR ar for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- VNRVPYPSPS CVKSEMGPWM ENYSGPYGDM RLDSTRDHVL PIDYYFPPQK TCLICGDEAS GCHYGALTCG SCKVFFKRAA EGKQKYLCAS RNDCTIDKFR RKNCPSCRLR KCYEAGMTLG ARKLKKLGNL KLQEEGENSS AGSPTEDPSQ KMTVSHIEGY ECQPIFLNVL EAIEPGVVCA GHDNNQPDS. It is sometimes possible for the material contained within the vial of "Androgen Receptor (AR), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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