rabbit anti-Human, Mouse ARMER Polyclonal Antibody | anti-ARL6IP1 antibody

ARMER, CT (ARL6IP, ARL6IP1, AIP1)

Cat. Num. AAA616934

• Gene Names: ARL6IP1; AIP1; ARMER; ARL6IP
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry
• Purity: Highly Purified; Purified by Ion Exchange chromatography.
• Synonyms: ARMER; Polyclonal Antibody; CT (ARL6IP; ARL6IP1; AIP1); Anti -ARMER; anti-ARL6IP1 antibody

• Host: rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: Human
• Purity/Purification: Highly Purified; Purified by Ion Exchange chromatography.

• Applicable Applications for anti-ARL6IP1 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot and Immunohistochemistry.; Dilution: Western Blot: 0.5-2ug/ml; Immunohistochemistry: 2.5ug/ml
• Immunogen: Synthetic peptide, KLH-conjugated. Epitope: peptide corresponding to 15 amino acids near the C-terminus of human ARMER
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Immunohistochemistry (IHC)

(Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with ARL6IP1 antibody at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Product Categories/Family for anti-ARL6IP1 antibody

Antibodies; Abs to Apoptosis

NCBI and Uniprot Product Information

• NCBI GI #: 24308007
• NCBI GeneID: 23204
• NCBI Accession #: NP_055976.1
• NCBI GenBank Nucleotide #: NM_015161.1
• UniProt Accession #: Q15041
• Molecular Weight: 23,363 Da
• NCBI Official Full Name: ADP-ribosylation factor-like protein 6-interacting protein 1
• NCBI Official Synonym Full Names: ADP-ribosylation factor-like 6 interacting protein 1
• NCBI Official Symbol: ARL6IP1
• NCBI Official Synonym Symbols: AIP1; ARMER; ARL6IP
• NCBI Protein Information: ADP-ribosylation factor-like protein 6-interacting protein 1; aip-1; ARL-6-interacting protein 1; apoptotic regulator in the membrane of the endoplasmic reticulum
• UniProt Protein Name: ADP-ribosylation factor-like protein 6-interacting protein 1
• Protein Family: ADP-ribosylation factor-like protein 6-interacting protein
• UniProt Gene Name: ARL6IP1
• UniProt Synonym Gene Names: ARL6IP; KIAA0069; ARL-6-interacting protein 1; Aip-1
• UniProt Entry Name: AR6P1_HUMAN

NCBI Description

This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Uniprot Description

ARL6IP: May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Belongs to the ARL6ip family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p12-p11.2

Cellular Component: membrane; integral to membrane; translocon complex; cytosol

Molecular Function: protein binding

Biological Process: cotranslational protein targeting to membrane

Disease: Spastic Paraplegia 61, Autosomal Recessive