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Western Blot (WB) (Western blot analysis of extracts from HEK-293 cells, using ARMC10 Antibody. The lane on the left was treated with blocking peptide.)

Rabbit ARMC10 Polyclonal Antibody | anti-ARMC10 antibody

ARMC10 Antibody

Gene Names
ARMC10; SVH; PNAS112; PNAS-112; PSEC0198
Reactivity
Human, Mouse, Rat
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
ARMC10; Polyclonal Antibody; ARMC10 Antibody; ARM10_HUMAN; Armadillo repeat containing 10; Armadillo repeat containing protein 10; Armadillo repeat-containing protein 10; ARMC 10; FLJ37850; MGC3195; PNAS112; Specific splicing variant involved in hepatocarcinogenesis; Splicing variant involved in hepatocarcinogenesis protein; SVH; anti-ARMC10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Clonality
Polyclonal
Isotype
IgG
Specificity
ARMC10 Antibody detects endogenous levels of ARMC10.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
308
Applicable Applications for anti-ARMC10 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human ARMC10.
Tissue Specificity
Expressed in all tissues tested with higher expression in placenta, liver, kidney, heart and brain.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Endoplasmic Reticulum
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from HEK-293 cells, using ARMC10 Antibody. The lane on the left was treated with blocking peptide.)

Western Blot (WB) (Western blot analysis of extracts from HEK-293 cells, using ARMC10 Antibody. The lane on the left was treated with blocking peptide.)

Western Blot (WB)

(Western blot analysis of extracts from Hybridoma cells, using ARMC10 Antibody. The lane on the left was treated with blocking peptide.)

Western Blot (WB) (Western blot analysis of extracts from Hybridoma cells, using ARMC10 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-ARMC10 antibody
Description: May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53.

Subunit Structure: Interacts with the DNA-binding domain of p53/TP53.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 37 kDa
Predicted: 38 kDa
NCBI Official Full Name
armadillo repeat-containing protein 10 isoform b
NCBI Official Synonym Full Names
armadillo repeat containing 10
NCBI Official Symbol
ARMC10
NCBI Official Synonym Symbols
SVH; PNAS112; PNAS-112; PSEC0198
NCBI Protein Information
armadillo repeat-containing protein 10
UniProt Protein Name
Armadillo repeat-containing protein 10
UniProt Gene Name
ARMC10
UniProt Synonym Gene Names
SVH
UniProt Entry Name
ARM10_HUMAN

NCBI Description

This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]

Uniprot Description

ARMC10: May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: endoplasmic reticulum membrane; mitochondrion; integral to membrane

Biological Process: regulation of growth

Research Articles on ARMC10

Similar Products

Product Notes

The ARMC10 armc10 (Catalog #AAA9611586) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARMC10 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's ARMC10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the ARMC10 armc10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARMC10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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