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Testing Data (Primary: Anti-SVH at 1/1000 dilution )

Rabbit SVH Polyclonal Antibody | anti-SVH antibody

SVH Polyclonal Antibody

Gene Names
ARMC10; SVH; PNAS112; PNAS-112; PSEC0198
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit
Applications
Western Blot
Purity
affinity purified by Protein A
Synonyms
SVH; Polyclonal Antibody; SVH Polyclonal Antibody; Armadillo repeat containing 10; Armadillo repeat containing protein 10; ARMC 10; ARMC10; PNAS112; Specific splicing variant involved in hepatocarcinogenesis; Splicing variant involved in hepatocarcinogenesis protein; ARM10_HUMAN; anti-SVH antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit
Clonality
Polyclonal
Specificity
SVH Polyclonal Antibody detects endogenous levels of SVH protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-SVH antibody
Western Blot (WB)
Application Notes
WB: 1:500-2000
Immunogen
KLH conjugated synthetic peptide derived from human SVH/ARMC10:131-240/343
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Testing Data

(Primary: Anti-SVH at 1/1000 dilution )

Testing Data (Primary: Anti-SVH at 1/1000 dilution )
Related Product Information for anti-SVH antibody
SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
24,757 Da
NCBI Official Full Name
armadillo repeat-containing protein 10 isoform b
NCBI Official Synonym Full Names
armadillo repeat containing 10
NCBI Official Symbol
ARMC10
NCBI Official Synonym Symbols
SVH; PNAS112; PNAS-112; PSEC0198
NCBI Protein Information
armadillo repeat-containing protein 10; specific splicing variant involved in hepatocarcinogenesis; splicing variant involved in hepatocarcinogenesis protein
UniProt Protein Name
Armadillo repeat-containing protein 10
UniProt Gene Name
ARMC10
UniProt Synonym Gene Names
SVH
UniProt Entry Name
ARM10_HUMAN

NCBI Description

This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]

Uniprot Description

ARMC10: May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: endoplasmic reticulum membrane; mitochondrion; integral to membrane

Biological Process: regulation of growth

Research Articles on SVH

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Product Notes

The SVH armc10 (Catalog #AAA3015497) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SVH Polyclonal Antibody reacts with Human, Mouse, Rat, Dog, Pig, Cow, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's SVH can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-2000. Researchers should empirically determine the suitability of the SVH armc10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SVH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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