Western Blot (WB)
(ARL6IP5 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the ARL6IP5 antibody detected the ARL6IP5 protein (arrow).)
Rabbit anti-Human, Mouse ARL6IP5 Polyclonal Antibody | anti-ARL6IP5 antibody
ARL6IP5, ID (ARL6IP5, DERP11, JWA, PRA2, PRAF3, PRA1 family protein 3, ADP-ribosylation factor-like protein 6-interacting protein 5, Cytoskeleton-related vitamin A-responsive protein, Dermal papilla-derived protein 11, GTRAP3-18, Glutamate transporter EAA
Gene Names
ARL6IP5; JWA; jmx; hp22; PRAF3; DERP11; HSPC127; addicsin; GTRAP3-18
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ARL6IP5; Polyclonal Antibody; ID (ARL6IP5; DERP11; JWA; PRA2; PRAF3; PRA1 family protein 3; ADP-ribosylation factor-like protein 6-interacting protein 5; Cytoskeleton-related vitamin A-responsive protein; Dermal papilla-derived protein 11; GTRAP3-18; Glutamate transporter EAA; Glutamate transporter EAAC1-interacting protein; JM5; Prenylated Rab acceptor protein 2; Protein JWa; Putative MAPK-activating protein PM27; anti-ARL6IP5 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-ARL6IP5 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
ARL6IP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-99 amino acids from the Central region of human ARL6IP5.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(ARL6IP5 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the ARL6IP5 antibody detected the ARL6IP5 protein (arrow).)
Western Blot (WB)
(ARL6IP5 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the ARL6IP5 antibody detected the ARL6IP5 protein (arrow).)
Related Product Information for anti-ARL6IP5 antibody
Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
Product Categories/Family for anti-ARL6IP5 antibody
References
Edenberg, H.J., et al. Alcohol. Clin. Exp. Res. 34(5):840-852(2010). Akiduki, S., et al. J. Biol. Chem. 283(46):31323-31332(2008). Ruggiero, A.M., et al. J. Biol. Chem. 283(10):6175-6183(2008). Watabe, M., et al. Mol. Pharmacol. 72(5):1103-1110(2007). Zhu, Y.J., et al. J. Toxicol. Environ. Health Part A 70(11):895-900(2007).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,615 Da
NCBI Official Full Name
PRA1 family protein 3
NCBI Official Synonym Full Names
ADP-ribosylation factor-like 6 interacting protein 5
NCBI Official Symbol
ARL6IP5
NCBI Official Synonym Symbols
JWA; jmx; hp22; PRAF3; DERP11; HSPC127; addicsin; GTRAP3-18
NCBI Protein Information
PRA1 family protein 3; JM5; aip-5; protein JWa; PRA1 domain family 3; ARL-6-interacting protein 5; dermal papilla derived protein 11; dermal papilla-derived protein 11; prenylated Rab acceptor protein 2; putative MAPK activating protein PM27; putative MAP
UniProt Protein Name
PRA1 family protein 3
Protein Family
UniProt Gene Name
ARL6IP5
UniProt Synonym Gene Names
DERP11; JWA; PRA2; PRAF3; ARL-6-interacting protein 5; Aip-5
UniProt Entry Name
PRAF3_HUMAN
NCBI Description
Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport. [provided by RefSeq, Jul 2008]
Uniprot Description
ARL6IP5: Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic. Belongs to the PRA1 family.
Protein type: Membrane protein, integral; Endoplasmic reticulum; Membrane protein, multi-pass; Cytoskeletal
Chromosomal Location of Human Ortholog: 3p14
Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane
Molecular Function: protein C-terminus binding
Biological Process: L-glutamate transport; positive regulation of apoptosis; positive regulation of caspase activity; negative regulation of transport; induction of apoptosis by oxidative stress; positive regulation of stress-activated MAPK cascade
Research Articles on ARL6IP5
Similar Products
Product Notes
The ARL6IP5 arl6ip5 (Catalog #AAA6275173) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARL6IP5, ID (ARL6IP5, DERP11, JWA, PRA2, PRAF3, PRA1 family protein 3, ADP-ribosylation factor-like protein 6-interacting protein 5, Cytoskeleton-related vitamin A-responsive protein, Dermal papilla-derived protein 11, GTRAP3-18, Glutamate transporter EAA reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ARL6IP5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ARL6IP5 arl6ip5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARL6IP5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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