Rabbit ARHGEF6 Polyclonal Antibody | anti-ARHGEF6 antibody

ARHGEF6 (COOL2, KIAA0006, PIXA, Rho Guanine Nucleotide Exchange Factor 6, Alpha-Pix, COOL-2, PAK-interacting Exchange Factor alpha, Rac/Cdc42 Guanine Nucleotide Exchange Factor 6) APC

Cat. Num. AAA6370310

• Gene Names: ARHGEF6; PIXA; COOL2; MRX46; Cool-2; alphaPIX; alpha-PIX
• Reactivity: Human, Rabbit
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ARHGEF6; Polyclonal Antibody; ARHGEF6 (COOL2; KIAA0006; PIXA; Rho Guanine Nucleotide Exchange Factor 6; Alpha-Pix; COOL-2; PAK-interacting Exchange Factor alpha; Rac/Cdc42 Guanine Nucleotide Exchange Factor 6) APC; anti-ARHGEF6 antibody

• Host: Rabbit
• Reactivity: Human, Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ARHGEF6.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
• Sequence Length: 776

• Applicable Applications for anti-ARHGEF6 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human ARHGEF6, aa1-776 (NP_004831).
• Immunogen Sequence: MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDPQTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCGRSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
• Conjugate: APC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of ARHGEF6 expression in transfected 293T cell line by ARHGEF6 polyclonal antibody. Lane 1: ARHGEF6 transfected lysate (87.5kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-ARHGEF6 antibody

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq].

Product Categories/Family for anti-ARHGEF6 antibody

Antibodies; GTPase; Rab; Ras; Rho Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 22027525
• NCBI GeneID: 9459
• NCBI Accession #: NP_004831
• NCBI GenBank Nucleotide #: NM_004840
• UniProt Accession #: Q15052
• NCBI Official Full Name: rho guanine nucleotide exchange factor 6 isoform 1
• NCBI Official Synonym Full Names: Rac/Cdc42 guanine nucleotide exchange factor 6
• NCBI Official Symbol: ARHGEF6
• NCBI Official Synonym Symbols: PIXA; COOL2; MRX46; Cool-2; alphaPIX; alpha-PIX
• NCBI Protein Information: rho guanine nucleotide exchange factor 6
• UniProt Protein Name: Rho guanine nucleotide exchange factor 6
• Protein Family: Rho guanine nucleotide exchange factor
• UniProt Gene Name: ARHGEF6
• UniProt Synonym Gene Names: COOL2; KIAA0006; PIXA
• UniProt Entry Name: ARHG6_HUMAN

NCBI Description

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008]