Structure
Silodosin Biochemical
Silodosin
Purity
>98% (HPLC)
Synonyms
Silodosin; KAD 3213; KMD 3213; Silodosin biochemical
Purity/Purification
>98% (HPLC)
Suitability
10mM in DMSO
Target
Adrenergic Receptor
Receptor
beta-adrenergicreceptor
Chemical Name
1H-Indole-7-carboxamide, 2, 3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2, 2, 2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]
SMILES
O=C(C1=CC(C[C@H](NCCOC2=CC=CC=C2OCC(F)(F)F)C)=CC3=C1N(CCCO)CC3)N
Molecular Formula
C25H32F3N3O4
CAS Number
160970-54-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Silodosin biochemical
A highly potent, uroselective alpha1a-adrenoceptor antagonist with Ki of 36 pM; displays 583- and 56-fold lower potency against alpha1b and alpha1d respectors, respectively; inhibits norepinephrine-induced increases intracellular Ca2+ concentrations in CHO cells with IC50 of 0.32nM; inhibits intraurethral pressure (IUP) response in vivo. Other Indication Approved
Product Categories/Family for Silodosin biochemical
References
1. Shibata K, et al. Mol Pharmacol. 1995 Aug; 48 (2):250-8.
2. Yamagishi R, et al. Eur J Pharmacol. 1996 Nov 7; 315 (1):73-9.
3. Yamada S, et al. Life Sci. 1998; 62 (17-18):1585-9.
4. Akiyama K, et al. J Pharmacol Exp Ther. 1999 Oct; 291 (1):81-91.
2. Yamagishi R, et al. Eur J Pharmacol. 1996 Nov 7; 315 (1):73-9.
3. Yamada S, et al. Life Sci. 1998; 62 (17-18):1585-9.
4. Akiyama K, et al. J Pharmacol Exp Ther. 1999 Oct; 291 (1):81-91.
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Product Notes
The Silodosin (Catalog #AAA3602319) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Silodosin, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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