Western Blot (WB)
(Western blot analysis of ARHGAP23 expression in A549 (A), NIH3T3 (B), HEK293T (C), mouse heart (D) whole cell lysates.)
Rabbit anti-Human, Mouse ARHGAP23 Polyclonal Antibody | anti-ARHGAP23 antibody
Anti-ARHGAP23 Antibody
Western Blot (WB)
(Western blot analysis of ARHGAP23 expression in A549 (A), NIH3T3 (B), HEK293T (C), mouse heart (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of ARHGAP23 expression in A549 (A), NIH3T3 (B), HEK293T (C), mouse heart (D) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of ARHGAP23 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of ARHGAP23 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
NCBI Description
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008]
Uniprot Description
ARHGAP23: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs; GAPs, Rac/Rho
Chromosomal Location of Human Ortholog: 17q12
Cellular Component: cytosol
Molecular Function: GTPase activator activity
Biological Process: positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction
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Product Notes
The ARHGAP23 arhgap23 (Catalog #AAA8242585) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ARHGAP23 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGAP23 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200). Researchers should empirically determine the suitability of the ARHGAP23 arhgap23 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGAP23, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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