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Testing Data

Rabbit ARHGAP15 Polyclonal Antibody | anti-ARHGAP15 antibody

Anti-ARHGAP15 Antibody

Gene Names
ARHGAP15; BM046
Reactivity
Human. Predicted: Mouse, Rat.
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
ARHGAP15; Polyclonal Antibody; Anti-ARHGAP15 Antibody; anti-ARHGAP15 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human. Predicted: Mouse, Rat.
Clonality
Polyclonal
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
475
Applicable Applications for anti-ARHGAP15 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:1,000-1:2,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal ARHGAP15 (1) antibody was raised against a recombinate human ARHGAP15 protein 277-475aa (BC016701).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Testing Data

Testing Data
Related Product Information for anti-ARHGAP15 antibody
RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]
References
(1) Leikauf,G.D., Concel,V.J., Liu,P. et al. Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1. Am. J. Respir. Crit. Care Med. 183 (11), 1499-1509 (2011).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
54,544 Da
NCBI Official Full Name
ARHGAP15
NCBI Official Synonym Full Names
Rho GTPase activating protein 15
NCBI Official Symbol
ARHGAP15
NCBI Official Synonym Symbols
BM046
NCBI Protein Information
rho GTPase-activating protein 15; rho-type GTPase-activating protein 15
UniProt Protein Name
Rho GTPase-activating protein 15
UniProt Gene Name
ARHGAP15
UniProt Entry Name
RHG15_HUMAN

NCBI Description

RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]

Uniprot Description

ARHGAP15: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction.

Protein type: GAPs, Rac/Rho; GAPs

Chromosomal Location of Human Ortholog: 2q22.2-q22.3

Cellular Component: membrane; cytosol

Biological Process: regulation of cell shape; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction

Research Articles on ARHGAP15

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Product Notes

The ARHGAP15 arhgap15 (Catalog #AAA415823) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ARHGAP15 Antibody reacts with Human. Predicted: Mouse, Rat. and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGAP15 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:1,000-1:2,000 Immunohistochemistry: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the ARHGAP15 arhgap15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGAP15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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