Western Blot (WB)
(WB Suggested Anti-NRD1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate)
Rabbit NRDC Polyclonal Antibody | anti-NRDC antibody
NRDC Antibody - middle region
Gene Names
NRDC; NRD1; hNRD1; hNRD2
Reactivity
Tested Reactivity: HumanPredicted Reactivity: Cow, Horse, Human, Pig
Applications
Western Blot
Purity
Affinity Purified
Synonyms
NRDC; Polyclonal Antibody; NRDC Antibody - middle region; anti-NRDC antibody
Host
Rabbit
Reactivity
Tested Reactivity: Human
Predicted Reactivity: Cow, Horse, Human, Pig
Predicted Reactivity: Cow, Horse, Human, Pig
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration
Batch dependent within range: 100ul at 0.5- 1mg/ml (varies by lot)
Sequence
Synthetic peptide located within the following region: GSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCI
Sequence Length
1151
Applicable Applications for anti-NRDC antibody
Western Blot (WB)
Homology
Cow: 93%; Horse: 86%; Human: 100%; Pig: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NRD1
Protein Size
1151 amino acids
Protein Interactions
FBXW11; UBC; rev; SETSIP; PUS1; P3H1; ELAC2; XPO5; NSUN2; PDIA6; YARS; DNAJC7; TSN; PPP3CA; PPP2R2A; PPP2CA; PFDN5; PFDN1; PPP1R12A; MSH2; PNKP; HSPB1; MOB2; MOB1A; STK3; NRD1; HIST2H3C; UACA; COBLL1; NCOR2; NCOR1; HDAC3; IQGAP1; MAD1L1; TBL1X; UIMC1; BTR
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(WB Suggested Anti-NRD1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate)
Western Blot (WB)
(WB Suggested Anti-NRD1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate)
Related Product Information for anti-NRDC antibody
This is a rabbit polyclonal antibody against NRD1. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.
Target Description: This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-NRDC antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
132kDa
NCBI Official Full Name
nardilysin isoform b
NCBI Official Synonym Full Names
nardilysin convertase
NCBI Official Symbol
NRDC
NCBI Official Synonym Symbols
NRD1; hNRD1; hNRD2
NCBI Protein Information
nardilysin
UniProt Protein Name
Nardilysin
Protein Family
UniProt Gene Name
NRD1
UniProt Synonym Gene Names
NRD convertase; NRD-C
UniProt Entry Name
NRDC_HUMAN
NCBI Description
This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Uniprot Description
Function: Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.
Catalytic activity: Hydrolysis of polypeptides, preferably at -Xaa-|-Arg-Lys-, and less commonly at -Arg-|-Arg-Xaa-, in which Xaa is not Arg or Lys.
Cofactor: Binds 1 zinc ion per subunit
By similarity.
Tissue specificity: Primarily in adult heart, skeletal muscle, and testis and at much lower levels in other tissues.
Sequence similarities: Belongs to the peptidase M16 family.
Research Articles on NRDC
Similar Products
Product Notes
The NRDC nrd1 (Catalog #AAA3214037) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NRDC Antibody - middle region reacts with Tested Reactivity: Human Predicted Reactivity: Cow, Horse, Human, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's NRDC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the NRDC nrd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: GSKMLSVHVV GYGKYELEED GTPSSEDSNS SCEVMQLTYL PTSPLLADCI. It is sometimes possible for the material contained within the vial of "NRDC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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