Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using ARC antibody.)
Rabbit anti-Human ARC Polyclonal Antibody | anti-ARC antibody
ARC Antibody
Immunohistochemistry: 1:50~1:100
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using ARC antibody.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using ARC antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells, using ARC antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells, using ARC antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells and A549 cells using ARC antibody. The lane on the left is treated with synthesized peptide.)
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells and A549 cells using ARC antibody. The lane on the left is treated with synthesized peptide.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Uniprot Description
ARC: 2 isoforms of the human protein are produced by alternative splicing. Isoform 1 may be involved in RNA splicing. Isoform 2 may inhibit apoptosis.
Protein type: Apoptosis; Nucleolus
Chromosomal Location of Human Ortholog: 16q22.1
Cellular Component: mitochondrion; cytoplasm; nucleolus; cytosol; sarcoplasm
Molecular Function: identical protein binding; protein binding; RNA binding; caspase inhibitor activity; calcium ion binding
Biological Process: mRNA splice site selection; response to injury involved in regulation of muscle adaptation; regulation of gene expression; RNA splicing; response to hypoxia; release of sequestered calcium ion by sarcoplasmic reticulum into cytosol; protein oligomerization; negative regulation of apoptosis
Disease: Myoclonus, Familial Cortical
Research Articles on ARC
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Product Notes
The ARC nol3 (Catalog #AAA9414995) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARC Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ARC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the ARC nol3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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