Western Blot (WB)
(Western blot analysis of Apolipoprotein L3 expression in A549 (A), PC12 (B), NS-1 (C) whole cell lysates.)
Rabbit Apolipoprotein L3 Polyclonal Antibody | anti-APOL3 antibody
Anti-Apolipoprotein L3 Antibody
Western Blot (WB)
(Western blot analysis of Apolipoprotein L3 expression in A549 (A), PC12 (B), NS-1 (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Apolipoprotein L3 expression in A549 (A), PC12 (B), NS-1 (C) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of Apolipoprotein L3 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of Apolipoprotein L3 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 22. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]
Uniprot Description
APOL3: May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles. Belongs to the apolipoprotein L family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid-binding
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: membrane; cytoplasm; extracellular region
Molecular Function: lipid transporter activity; signal transducer activity; lipid binding
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; lipoprotein metabolic process; signal transduction; lipid transport; inflammatory response
Research Articles on APOL3
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Product Notes
The APOL3 apol3 (Catalog #AAA8222382) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Apolipoprotein L3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Apolipoprotein L3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB (1/500 - 1/1000), IHC (1/100 - 1/200). Researchers should empirically determine the suitability of the APOL3 apol3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Apolipoprotein L3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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