Western Blot (WB)
(Anti-APC2 Antibody (N-Term) at 1:2000 dilution + Hela whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 244 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human APC2 Polyclonal Antibody | anti-APC2 antibody
APC2 Antibody (N-Term)
Western Blot (WB)
(Anti-APC2 Antibody (N-Term) at 1:2000 dilution + Hela whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 244 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(Anti-APC2 Antibody (N-Term) at 1:2000 dilution + Hela whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 244 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
NCBI and Uniprot Product Information
NCBI Description
APCL: Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling. Belongs to the adenomatous polyposis coli (APC) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, peripheral
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: microtubule cytoskeleton; Golgi membrane; Golgi apparatus; cytoplasmic microtubule; perinuclear region of cytoplasm; cytoplasm; actin filament; catenin complex; beta-catenin destruction complex
Molecular Function: protein binding; gamma-catenin binding; microtubule binding; beta-catenin binding
Biological Process: cell proliferation; cell migration; Wnt receptor signaling pathway; negative regulation of microtubule depolymerization; regulation of cell differentiation; positive regulation of protein catabolic process; cell fate specification; pattern specification process
Uniprot Description
APCL: Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling. Belongs to the adenomatous polyposis coli (APC) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, peripheral
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: actin filament; beta-catenin destruction complex; catenin complex; cytoplasm; cytoplasmic microtubule; Golgi apparatus; microtubule cytoskeleton; perinuclear region of cytoplasm
Molecular Function: beta-catenin binding; gamma-catenin binding; microtubule binding; protein binding
Biological Process: cell fate specification; cell migration; cell proliferation; negative regulation of microtubule depolymerization; pattern specification process; positive regulation of protein catabolic process; regulation of cell differentiation; Wnt receptor signaling pathway
Research Articles on APC2
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Product Notes
The APC2 apc2 (Catalog #AAA9216097) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC2 Antibody (N-Term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's APC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB ~~ 1:2000. Researchers should empirically determine the suitability of the APC2 apc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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