Testing Data
Rabbit APBB2 Polyclonal Antibody | anti-APBB2 antibody
Anti-APBB2 Antibody
Western blot analysis: 1:500-1:1,000
Optimal dilutions/concentrations should be determined by the end user
Testing Data
Testing Data
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Uniprot Description
APBB2: May modulate the internalization of beta-amyloid precursor protein. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 4p13
Cellular Component: growth cone; membrane; lamellipodium; cytoplasm; synapse; nucleus
Molecular Function: protein binding; beta-amyloid binding; transcription factor binding
Biological Process: axon guidance; extracellular matrix organization and biogenesis; regulation of transcription, DNA-dependent; positive regulation of apoptosis; neuron migration; negative regulation of cell growth; cell cycle arrest; negative regulation of apoptosis
Disease: Alzheimer Disease
Research Articles on APBB2
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Product Notes
The APBB2 apbb2 (Catalog #AAA417769) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-APBB2 Antibody reacts with Human. Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's APBB2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1:1,000 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the APBB2 apbb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APBB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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