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Immunohistochemistry (IHC) (Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit FE65L1/APBB2 Polyclonal Antibody | anti-FE65L1/APBB2 antibody

Anti-FE65L1/APBB2 Antibody (aa475-524)

Gene Names
APBB2; FE65L; FE65L1
Reactivity
Human
Predicted: Mouse
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
FE65L1/APBB2; Polyclonal Antibody; Anti-FE65L1/APBB2 Antibody (aa475-524); Rabbit Polyclonal to Human FE65L1/APBB2; APBB2; Fe65-like 1; FE65L1; Fe65-like; FE65L; Protein Fe65-like 1; anti-FE65L1/APBB2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
APBB2 Antibodyantibody detects endogenous levels of APBB2.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Sequence Length
758
Applicable Applications for anti-FE65L1/APBB2 antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
ELISA: 1:10000
IHC-P: 1:50
WB: 1:500-1:1000
Immunogen
Synthetic peptide from human APBB2 (aa475-524).
Conjugation
Unconjugated
Epitope
aa475-524
Preparation and Storage
Store at -20 degree C.

Immunohistochemistry (IHC)

(Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB)

(Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB) (Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot of the lysates from HepG2 cells using APBB2 antibody.)

Western Blot (WB) (Western blot of the lysates from HepG2 cells using APBB2 antibody.)
Related Product Information for anti-FE65L1/APBB2 antibody
FE65L1/APBB2 interacts with the cytoplasmic domains of amyloid beta(A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, whichare thought to function in signal transduction. Polymorphisms in thisgene have been associated with Alzheimer's disease. Alternative splicingresults in multiple transcript variants.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
323
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
83,445 Da
NCBI Official Full Name
amyloid-beta A4 protein-binding family B member 2 isoform b
NCBI Official Synonym Full Names
amyloid beta precursor protein binding family B member 2
NCBI Official Symbol
APBB2
NCBI Official Synonym Symbols
FE65L; FE65L1
NCBI Protein Information
amyloid-beta A4 precursor protein-binding family B member 2
UniProt Protein Name
Amyloid-beta A4 precursor protein-binding family B member 2
UniProt Gene Name
APBB2
UniProt Synonym Gene Names
FE65L; FE65L1

NCBI Description

The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Uniprot Description

May modulate the internalization of amyloid-beta precursor protein.

Research Articles on FE65L1/APBB2

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Product Notes

The FE65L1/APBB2 apbb2 (Catalog #AAA2401289) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FE65L1/APBB2 Antibody (aa475-524) reacts with Human Predicted: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FE65L1/APBB2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 1:10000 IHC-P: 1:50 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the FE65L1/APBB2 apbb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FE65L1/APBB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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