Western Blot (WB)
(Figure-1: Western blot analysis of AP3M1. Anti-AP3M1 antibody (11-8123) was used at 1 ug/ml on (1) PC3 and (2) A375 lysates.)
Rabbit anti-Human AP3M1 Polyclonal Antibody | anti-AP3M1 antibody
Polyclonal Antibody to AP3M1
For long-term storage, store at -20 degree C.
Avoid repeat freezing and thawing.
Western Blot (WB)
(Figure-1: Western blot analysis of AP3M1. Anti-AP3M1 antibody (11-8123) was used at 1 ug/ml on (1) PC3 and (2) A375 lysates.)
Western Blot (WB)
(Figure-1: Western blot analysis of AP3M1. Anti-AP3M1 antibody (11-8123) was used at 1 ug/ml on (1) PC3 and (2) A375 lysates.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Uniprot Description
AP3M1: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Belongs to the adaptor complexes medium subunit family.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 10q22.2
Cellular Component: Golgi apparatus; clathrin adaptor complex; cytoplasmic vesicle membrane; lysosomal membrane; lysosome
Molecular Function: protein binding; Rab GTPase binding
Biological Process: protein targeting to lysosome; anterograde synaptic vesicle transport; anterograde axon cargo transport
Research Articles on AP3M1
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Product Notes
The AP3M1 ap3m1 (Catalog #AAA669326) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to AP3M1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AP3M1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1-2 ug/ml. Researchers should empirically determine the suitability of the AP3M1 ap3m1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AP3M1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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