Rabbit anti-Human ANKFY1 Polyclonal Antibody | anti-ANKFY1 antibody

ANKFY1, CT (ANKFY1, ANKHZN, KIAA1255, Ankyrin repeat and FYVE domain-containing protein 1, Ankyrin repeats hooked to a zinc finger motif) (MaxLight 490)

Cat. Num. AAA6273527

• Gene Names: ANKFY1; ANKHZN; BTBD23; ZFYVE14
• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ANKFY1; Polyclonal Antibody; CT (ANKFY1; ANKHZN; KIAA1255; Ankyrin repeat and FYVE domain-containing protein 1; Ankyrin repeats hooked to a zinc finger motif) (MaxLight 490); Ankyrin repeats hooked to a zinc finger motif; anti-ANKFY1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

• Applicable Applications for anti-ANKFY1 antibody: Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: FC/FACS: 1:10-50; FLISA: 1:1,000; IHC: 1:50-100; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: ANKFY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443~473 amino acids from the C-terminal region of human ANKFY1.
• Conjugate: MaxLight490
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Related Product Information for anti-ANKFY1 antibody

ANKFY1 encodes a cytoplasmic protein that contains a coiled-coil structure and a BTB/POZ domain at its N-terminus, ankyrin repeats in the middle portion, and a FYVE-finger motif at its C-terminus. This protein belongs to a subgroup of double zinc finger proteins which may be involved in vesicle or protein transport.

Product Categories/Family for anti-ANKFY1 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

References

Bouslam, N., et al. Hum. Genet. 121 (3-4), 413-420 (2007). Schnatwinkel, C., et al. PLoS Biol. 2 (9), E261 (2004).

NCBI and Uniprot Product Information

• NCBI GI #: 384367970
• NCBI GeneID: 51479
• NCBI Accession #: NP_001244928.1
• NCBI GenBank Nucleotide #: NM_001257999.1
• UniProt Accession #: Q9P2R3; Q5RKV4; Q9ULG5; A8KA65
• Molecular Weight: 128,399 Da
• NCBI Official Full Name: ankyrin repeat and FYVE domain-containing protein 1 isoform 3
• NCBI Official Synonym Full Names: ankyrin repeat and FYVE domain containing 1
• NCBI Official Symbol: ANKFY1
• NCBI Official Synonym Symbols: ANKHZN; BTBD23; ZFYVE14
• NCBI Protein Information: ankyrin repeat and FYVE domain-containing protein 1; Rabankyrin-5; ankyrin repeat hooked to zinc finger motif; ankyrin repeats hooked to a zinc finger motif
• UniProt Protein Name: Ankyrin repeat and FYVE domain-containing protein 1
• Protein Family: Rabankyrin
• UniProt Gene Name: ANKFY1
• UniProt Synonym Gene Names: ANKHZN; KIAA1255
• UniProt Entry Name: ANFY1_HUMAN

NCBI Description

This gene encodes a cytoplasmic protein that contains a coiled-coil structure and a BTB/POZ domain at its N-terminus, ankyrin repeats in the middle portion, and a FYVE-finger motif at its C-terminus. This protein belongs to a subgroup of double zinc finger proteins which may be involved in vesicle or protein transport. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Apr 2012]

Uniprot Description

ANKFY1: a cytoplasmic protein that contains a coiled-coil structure and a BTB/POZ domain at its N-terminus, ankyrin repeats in the middle portion, and a FYVE-finger motif at its C-terminus. This protein belongs to a subgroup of double zinc finger proteins which may be involved in vesicle or protein transport. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Apr 2012]

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: membrane; retromer complex; lysosomal membrane; early endosome; endosome membrane

Molecular Function: protein binding; metal ion binding; Rab GTPase binding

Biological Process: endosomal vesicle fusion; endocytosis; positive regulation of pinocytosis; retrograde transport, endosome to Golgi; endosome localization