anti-Human Angiotensin II Type 2 Receptor Polyclonal Antibody | anti-AGTR2 antibody
Anti - Angiotensin II Type 2 Receptor (AT2)
Gene Names
AGTR2; AT2; ATGR2; MRX88
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Serum
Synonyms
Angiotensin II Type 2 Receptor; Polyclonal Antibody; Anti - Angiotensin II Type 2 Receptor (AT2); Angiotensin II Type 2 Receptor (AT2); anti-AGTR2 antibody
Host
Host: Chicken
Source: Human
Source: Human
Reactivity
Human
Clonality
Polyclonal
Isotype
IgY
Specificity
Recognizes human Angiotensin II Type 2 Receptor. No sequence homology with other G-protein coupled receptors. Species Sequence Homology
Purity/Purification
Serum
Form/Format
Serum
Supplied as a liquid, neat serum, 0.1% sodium azide, 40% glycerol.
Supplied as a liquid, neat serum, 0.1% sodium azide, 40% glycerol.
Sequence Length
363
Applicable Applications for anti-AGTR2 antibody
ELISA, Western Blot
Application Notes
Suitable for use in ELISA, Western Blot. Other applications not tested.
Dilution: Western Blot: 1:1000-1:5000 (ECL). Detects a band at ~45kD.
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Optimal dilutions to be determined by the researcher.
Dilution: Western Blot: 1:1000-1:5000 (ECL). Detects a band at ~45kD.
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Optimal dilutions to be determined by the researcher.
Immunogen
Synthetic peptide consisting of 18aa sequence mapping near the C-terminus of human AT2 (KLH coupled). This peptide is predicted to be cytoplasmic.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-AGTR2 antibody
Angiotensin II mediates its action by interacting with membrane receptor, Angiotensin II type 1 receptors. The signal is transmitted via G-proteins that activates a phosphatidylinositol-calcium second messenger system. ATII receptors are integral membrane proteins of approx. 359-363aa and predicted to contain at least 7 transmembrane domains. The N and C-terminus are predicted to extracellular and cytoplasmic, respectively. Three isoforms of ATII receptors have been cloned. In rat type 1a (359aa) is expressed in the liver kidney, aorta, lung, uterus, ovary, spleen, heart, adrenal and vascular smooth muscles (1). Rat Type 1b (also known as AT3; 359aa) is found in liver, kidney, and aorta (2). Type 1c (177aa) has been detected in brain, kidney, liver, spleen and lung (3).
Product Categories/Family for anti-AGTR2 antibody
References
• 1. Martin, M.M., et al., BBRC 209: 554-562 (1995).
• 2. Chassagne, C., et al., Genomics 25: 601-603 (1995).
• 3. Koike, G., et al., BBRC 203: 1842-50 (1994).
• 4. Tsuzuki, S., et al., BBRC 200: 1449-54 (1994).
• 5. Martin, M.M., et al., BBRC 205: 645-651 (1994).
• 6. Lazard, D., et al., Receptor Channels 2: 271-280 (1994).
• 2. Chassagne, C., et al., Genomics 25: 601-603 (1995).
• 3. Koike, G., et al., BBRC 203: 1842-50 (1994).
• 4. Tsuzuki, S., et al., BBRC 200: 1449-54 (1994).
• 5. Martin, M.M., et al., BBRC 205: 645-651 (1994).
• 6. Lazard, D., et al., Receptor Channels 2: 271-280 (1994).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
41,184 Da
NCBI Official Full Name
angiotensin II type 2 receptor
NCBI Official Synonym Full Names
angiotensin II receptor, type 2
NCBI Official Symbol
AGTR2
NCBI Official Synonym Symbols
AT2; ATGR2; MRX88
NCBI Protein Information
type-2 angiotensin II receptor; OTTHUMP00000023878; angiotensin II type-2 receptor
UniProt Protein Name
Type-2 angiotensin II receptor
Protein Family
UniProt Gene Name
AGTR2
UniProt Entry Name
AGTR2_HUMAN
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Product Notes
The AGTR2 agtr2 (Catalog #AAA621023) is an Antibody produced from Host: Chicken Source: Human and is intended for research purposes only. The product is available for immediate purchase. The Anti - Angiotensin II Type 2 Receptor (AT2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Angiotensin II Type 2 Receptor can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Suitable for use in ELISA, Western Blot. Other applications not tested. Dilution: Western Blot: 1:1000-1:5000 (ECL). Detects a band at ~45kD. ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the AGTR2 agtr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Angiotensin II Type 2 Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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