Rabbit anti-Human Amyloid Protein-binding Protein 2 Polyclonal Antibody | anti-APPBP2 antibody

Amyloid Protein-binding Protein 2, CT (Amyloid beta Precursor Protein-binding Protein 2, APPBP2, APP-BP2, HS.84084, KIAA0228, Protein Interacting with APP Tail 1, PAT1)

Cat. Num. AAA627122

• Gene Names: APPBP2; PAT1; HS.84084; KIAA0228
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: Amyloid Protein-binding Protein 2; Polyclonal Antibody; CT (Amyloid beta Precursor Protein-binding Protein 2; APPBP2; APP-BP2; HS.84084; KIAA0228; Protein Interacting with APP Tail 1; PAT1); Anti -Amyloid Protein-binding Protein 2; anti-APPBP2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human APPBP2.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.09% sodium azide.

• Applicable Applications for anti-APPBP2 antibody: ELISA (EL/EIA), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA and Immunohistochemistry.; Dilution: ELISA: 1:1,000; Immunohistochemistry: 1:10-1:50
• Immunogen: Synthetic peptide selected from the C-terminal region of human APPBP2 (KLH).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-APPBP2 antibody

APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This protein has been found to be highly expressed in breast cancer.

Product Categories/Family for anti-APPBP2 antibody

Antibodies; Abs to Neuroscience

NCBI and Uniprot Product Information

• NCBI GI #: 18104962
• NCBI GeneID: 10513
• NCBI Accession #: NP_006371.2
• NCBI GenBank Nucleotide #: NM_006380.2
• UniProt Accession #: Q92624; O95095; Q8WVC9; A8K862
• Molecular Weight: 66,853 Da
• NCBI Official Full Name: amyloid protein-binding protein 2
• NCBI Official Synonym Full Names: amyloid beta precursor protein (cytoplasmic tail) binding protein 2
• NCBI Official Symbol: APPBP2
• NCBI Official Synonym Symbols: PAT1; HS.84084; KIAA0228
• NCBI Protein Information: amyloid protein-binding protein 2; APP-BP2; protein interacting with APP tail 1; amyloid beta precursor protein-binding protein 2
• UniProt Protein Name: Amyloid protein-binding protein 2
• Protein Family: Amyloid protein-binding protein
• UniProt Gene Name: APPBP2
• UniProt Synonym Gene Names: KIAA0228; PAT1
• UniProt Entry Name: APBP2_HUMAN

NCBI Description

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq]

Uniprot Description

APPBP2: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

Protein type: Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 17q23.2

Cellular Component: microtubule; microtubule associated complex; cytoplasmic vesicle membrane; cytoplasm; nucleus

Molecular Function: protein binding; microtubule motor activity

Biological Process: intracellular protein transport; intracellular transport; metabolic process