Western Blot (WB)
(APPBP2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the APPBP2 antibody detected the APPBP2 protein (arrow).)
Rabbit anti-Human APPBP2 Polyclonal Antibody | anti-APPBP2 antibody
APPBP2, ID (APPBP2, KIAA0228, PAT1, Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, Protein interacting with APP tail 1) (APC)
Gene Names
APPBP2; PAT1; HS.84084
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
APPBP2; Polyclonal Antibody; ID (APPBP2; KIAA0228; PAT1; Amyloid protein-binding protein 2; Amyloid beta precursor protein-binding protein 2; Protein interacting with APP tail 1) (APC); Protein interacting with APP tail 1; anti-APPBP2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-APPBP2 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
APPBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-271 amino acids from the Central region of human APPBP2.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(APPBP2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the APPBP2 antibody detected the APPBP2 protein (arrow).)
Western Blot (WB)
(APPBP2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the APPBP2 antibody detected the APPBP2 protein (arrow).)
Related Product Information for anti-APPBP2 antibody
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.
Product Categories/Family for anti-APPBP2 antibody
References
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009). Benboudjema, L., et al. J. Virol. 77(17):9192-9203(2003). Gao, Y., et al. Proc. Natl. Acad. Sci. U.S.A. 98(26):14979-14984(2001). Monni, O., et al. Proc. Natl. Acad. Sci. U.S.A. 98(10):5711-5716(2001). Barlund, M., et al. Cancer Res. 60(19):5340-5344(2000).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
66,853 Da
NCBI Official Full Name
amyloid protein-binding protein 2
NCBI Official Synonym Full Names
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
NCBI Official Symbol
APPBP2
NCBI Official Synonym Symbols
PAT1; HS.84084
NCBI Protein Information
amyloid protein-binding protein 2; APP-BP2; protein interacting with APP tail 1; amyloid beta precursor protein-binding protein 2
UniProt Protein Name
Amyloid protein-binding protein 2
Protein Family
UniProt Gene Name
APPBP2
UniProt Synonym Gene Names
KIAA0228; PAT1; APP-BP2
UniProt Entry Name
APBP2_HUMAN
NCBI Description
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
APPBP2: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.
Protein type: Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 17q23.2
Cellular Component: microtubule; microtubule associated complex; cytoplasmic vesicle membrane; cytoplasm; nucleus
Molecular Function: protein binding; microtubule motor activity
Biological Process: intracellular protein transport; intracellular transport; metabolic process
Research Articles on APPBP2
Similar Products
Product Notes
The APPBP2 appbp2 (Catalog #AAA6274578) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APPBP2, ID (APPBP2, KIAA0228, PAT1, Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, Protein interacting with APP tail 1) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's APPBP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the APPBP2 appbp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APPBP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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