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Sheep Alpha 2 HS glycoprotein Polyclonal Antibody | anti-AHSG antibody

Alpha 2 HS glycoprotein antibody

Applications
User optimized
Purity
> 95% pure
Affinity purified using solid phase Human Alpha-2-HS Glycoprotein
Synonyms
Alpha 2 HS glycoprotein; Polyclonal Antibody; Alpha 2 HS glycoprotein antibody; Polyclonal Alpha 2 HS glycoprotein; Anti-Alpha 2 HS glycoprotein; Alpha HS glycoprotein 2; Alpha HS glycoprotein -2; anti-AHSG antibody
Ordering
For Research Use Only!
Host
Sheep
Clonality
Polyclonal
Specificity
Alpha 2 HS glycoprotein antibody was raised against Human Alpha-2-HS Glycoprotein.
Purity/Purification
> 95% pure
Affinity purified using solid phase Human Alpha-2-HS Glycoprotein
Form/Format
Clear, colorless liquid, 0.2 um filtered, containing 10 mM Sodium Phosphate, 0.15 M Sodium Chloride and 0.05% (w/v) Sodium Azide. Protease/IgG free.
Concentration
>4.5 mg/ml (varies by lot)
Sequence Length
367
Applicable Applications for anti-AHSG antibody
User optimized
Application Notes
The optimal working dilution should be determined by the end user
Source Note
Sheep serum was obtained from healthy animals of UK origin and under the care of a registered veterinarian.
Biological Significance
Alpha2-HS glycoprotein, a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues.
Immunogen
Human Alpha-2-HS Glycoprotein
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-AHSG antibody
Affinity purified Sheep polyclonal Alpha 2 HS glycoprotein antibody
Product Categories/Family for anti-AHSG antibody

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
39,325 Da
NCBI Official Full Name
alpha-2-HS-glycoprotein
UniProt Protein Name
Alpha-2-HS-glycoprotein
Protein Family
UniProt Gene Name
AHSG
UniProt Synonym Gene Names
FETUA
UniProt Entry Name
FETUA_HUMAN

Uniprot Description

FETUA: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. Belongs to the fetuin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3q27

Cellular Component: extracellular space; extracellular region

Molecular Function: kinase inhibitor activity; cysteine protease inhibitor activity

Biological Process: negative regulation of bone mineralization; pinocytosis; ossification; positive regulation of phagocytosis; regulation of inflammatory response; acute-phase response; negative regulation of phosphorylation; negative regulation of insulin receptor signaling pathway; skeletal development; regulation of bone mineralization

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Product Notes

The Alpha 2 HS glycoprotein ahsg (Catalog #AAA833959) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Alpha 2 HS glycoprotein can be used in a range of immunoassay formats including, but not limited to, User optimized. The optimal working dilution should be determined by the end user. Researchers should empirically determine the suitability of the Alpha 2 HS glycoprotein ahsg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Alpha 2 HS glycoprotein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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