Western Blot (WB)
(ALKBH5 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ALKBH5 Antibody detected the ALKBH5 protein (arrow).)
Rabbit ALKBH5 Polyclonal Antibody | anti-ALKBH5 antibody
ALKBH5 Antibody (Center)
Gene Names
ALKBH5; ABH5; OFOXD; OFOXD1
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ALKBH5; Polyclonal Antibody; ALKBH5 Antibody (Center); RNA demethylase ALKBH5; 11411-; Alkylated DNA repair protein alkB homolog 5; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5; ABH5; OFOXD1; anti-ALKBH5 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ALKBH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-330 amino acids from the Central region of human ALKBH5.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.41 (varies by lot)
Sequence Positions
302-330
Sequence Length
383
Applicable Applications for anti-ALKBH5 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(ALKBH5 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ALKBH5 Antibody detected the ALKBH5 protein (arrow).)
Western Blot (WB)
(ALKBH5 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ALKBH5 Antibody detected the ALKBH5 protein (arrow).)
Related Product Information for anti-ALKBH5 antibody
Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Bi, W., et al. Genome Res. 12(5):713-728(2002)
Bi, W., et al. Genome Res. 12(5):713-728(2002)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44256
NCBI Official Full Name
RNA demethylase ALKBH5
NCBI Official Synonym Full Names
alkB homolog 5, RNA demethylase
NCBI Official Symbol
ALKBH5
NCBI Official Synonym Symbols
ABH5; OFOXD; OFOXD1
NCBI Protein Information
RNA demethylase ALKBH5
UniProt Protein Name
RNA demethylase ALKBH5
Protein Family
UniProt Gene Name
ALKBH5
UniProt Synonym Gene Names
ABH5; OFOXD1
UniProt Entry Name
ALKB5_HUMAN
Uniprot Description
ALKBH5: a protein contaning a 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily domain. May be involved in DNA alkylation damage repair
Protein type: EC 1.14.11.-; Membrane protein, integral; DNA repair, damage; RNA-binding; Oxidoreductase
Chromosomal Location of Human Ortholog: 17p11.2|17p11.2
Cellular Component: nuclear speck; nucleus
Molecular Function: metal ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Biological Process: mRNA export from nucleus; response to hypoxia; spermatogenesis; cell differentiation; mRNA processing
Research Articles on ALKBH5
Similar Products
Product Notes
The ALKBH5 alkbh5 (Catalog #AAA9214620) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 302-330. The ALKBH5 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's ALKBH5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the ALKBH5 alkbh5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALKBH5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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