Western Blot (WB)
((0. 01ug/ml) staining of Mouse Eye lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat ALDH3A1 Polyclonal Antibody | anti-ALDH3A1 antibody
Goat anti-ALDH3A1 Antibody
Immunohistochemistry: In paraffin embedded Human Lung shows strong staining of the respiratory epithelium of the tracheal wall. Recommended concentration, 3-5ug/ml.
Western Blot: Approx 55kDa band observed in Mouse Eye lysates (calculated MW of 50.5kDa according to Mouse NP_031462.2). Recommended concentration: 0.01-0.03ug/ml.
Western Blot (WB)
((0. 01ug/ml) staining of Mouse Eye lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((0. 01ug/ml) staining of Mouse Eye lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Immunohistochemistry (IHC)
((3.8ug/ml) staining of paraffin embedded Human Lung. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.)
Immunohistochemistry (IHC)
((3.8ug/ml) staining of paraffin embedded Human Lung. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.)
NCBI and Uniprot Product Information
NCBI Description
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Uniprot Description
ALDH3A1: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. Belongs to the aldehyde dehydrogenase family.
Protein type: EC 1.2.1.5; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - metabolism by cytochrome P450; Amino Acid Metabolism - tyrosine
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; extracellular space; integral to membrane; intracellular membrane-bound organelle; nucleoplasm; plasma membrane
Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity; alcohol dehydrogenase (NADP+) activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; benzaldehyde dehydrogenase (NAD+) activity; protein binding
Biological Process: aging; aldehyde metabolic process; positive regulation of cell proliferation; response to cAMP; response to drug; response to glucocorticoid stimulus; response to hypoxia; response to nutrient; xenobiotic metabolic process
Research Articles on ALDH3A1
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Product Notes
The ALDH3A1 aldh3a1 (Catalog #AAA422394) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-ALDH3A1 Antibody reacts with Tested: Human, Mouse; Expected from sequence similarity: Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ALDH3A1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA: Antibody detection limit dilution 1: 32000. Immunohistochemistry: In paraffin embedded Human Lung shows strong staining of the respiratory epithelium of the tracheal wall. Recommended concentration, 3-5ug/ml. Western Blot: Approx 55kDa band observed in Mouse Eye lysates (calculated MW of 50.5kDa according to Mouse NP_031462.2). Recommended concentration: 0.01-0.03ug/ml. Researchers should empirically determine the suitability of the ALDH3A1 aldh3a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: RYPPSPAKMT QH. It is sometimes possible for the material contained within the vial of "ALDH3A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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