Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Raji and Jurkat cell Amount of lysate: 40ug per lane Primary antibody: 1/175 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 seconds)
Rabbit anti-Human AKR1B10 Polyclonal Antibody | anti-AKR1B10 antibody
AKR1B10 Antibody
Immunohistochemistry: 1:25-1:100
Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Raji and Jurkat cell Amount of lysate: 40ug per lane Primary antibody: 1/175 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 seconds)
Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Raji and Jurkat cell Amount of lysate: 40ug per lane Primary antibody: 1/175 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 seconds)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/20.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/20.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
AKR1B10: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. Belongs to the aldo/keto reductase family.
Protein type: Carbohydrate Metabolism - fructose and mannose; EC 1.1.1.-; Oxidoreductase; Lipid Metabolism - linoleic acid; EC 1.1.1.21; Carbohydrate Metabolism - butanoate
Chromosomal Location of Human Ortholog: 7q33
Cellular Component: lysosome; cytosol
Molecular Function: protein binding; aldo-keto reductase activity; indanol dehydrogenase activity; geranylgeranyl reductase activity; retinal dehydrogenase activity
Biological Process: steroid metabolic process; phototransduction, visible light; digestion; farnesol catabolic process; aldehyde metabolic process; retinoid metabolic process
Research Articles on AKR1B10
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Product Notes
The AKR1B10 akr1b10 (Catalog #AAA9408759) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AKR1B10 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AKR1B10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:200-1:1000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the AKR1B10 akr1b10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AKR1B10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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