Rabbit AKAP95 AKAP8 Polyclonal Antibody | anti-AKAP95 antibody

AKAP95 AKAP8 Antibody FITC Conjugated

Cat. Num. AAA9460672

• Gene Names: AKAP8; AKAP-8; AKAP95; AKAP 95; AKAP-95
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence
• Purity: Purified by Protein A
• Synonyms: AKAP95 AKAP8; Polyclonal Antibody; AKAP95 AKAP8 Antibody FITC Conjugated; AKAP8; A-kinase Anchoring Protein 95; CCK 1; CCK1; CCL 28; Chemokine C-C mot ligand 28; MEC; Mucosae associated epithelial chemokine; SCYA28; Small inducible cytokine A28; AKP8L_HUMAN AKAP95 AKAP8; anti-AKAP95 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A
• Form/Format: 10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
• Concentration: 1mgml (varies by lot)

• Applicable Applications for anti-AKAP95 antibody: Immunofluorescence (IF)
• Application Notes: IF: 1:50-200
• Conjugation: FITC
• Excitation Emission: 494nm 518nm
• Immunogen: KLH conjugated synthetic peptide derived from human AKAP95
• Preparation and Storage: Store at 4 degree C for 12 months.

Related Product Information for anti-AKAP95 antibody

This protein belongs to the subfamily of small cytokine CC proteins. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. This cytokine displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils and binds to chemokine receptors CCR3 and CCR10. It induces calcium mobilization in a dose-dependent manner. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs.

Product Categories/Family for anti-AKAP95 antibody

Conjugated Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 5031579
• NCBI GeneID: 10270
• NCBI Accession #: NP_005849.1
• NCBI GenBank Nucleotide #: NM_005858.3
• UniProt Accession #: O43823
• Molecular Weight: 76,108 Da
• NCBI Official Full Name: A-kinase anchor protein 8
• NCBI Official Synonym Full Names: A kinase (PRKA) anchor protein 8
• NCBI Official Symbol: AKAP8
• NCBI Official Synonym Symbols: AKAP-8; AKAP95; AKAP 95; AKAP-95
• NCBI Protein Information: A-kinase anchor protein 8; A-kinase anchor protein, 95kDa
• UniProt Protein Name: A-kinase anchor protein 8
• UniProt Gene Name: AKAP8
• UniProt Synonym Gene Names: AKAP95; AKAP-8; AKAP 95
• UniProt Entry Name: AKAP8_HUMAN

NCBI Description

This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]

Uniprot Description

AKAP8: Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II). Belongs to the AKAP95 family.

Protein type: Mitochondrial; Cell cycle regulation; RNA-binding; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: nucleoplasm; Golgi apparatus; nuclear matrix; mitochondrion; membrane; condensed chromosome; female pronucleus; nucleus

Molecular Function: zinc ion binding; double-stranded DNA binding

Biological Process: mitosis; mitotic chromosome condensation; signal transduction