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Testing Data

Rabbit AIF1 Polyclonal Antibody | anti-AIF1 antibody

AIF1 Antibody

Gene Names
AIF1; IBA1; IRT1; AIF-1; IRT-1
Reactivity
Human
Predicted: Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
AIF1; Polyclonal Antibody; AIF1 Antibody; anti-AIF1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by peptide affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
147
Applicable Applications for anti-AIF1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Testing Data

Testing Data
Related Product Information for anti-AIF1 antibody
Rabbit polyclonal AIF1 (1) antibody was raised against a peptide from C terminal residues of human AIF1 protein.
References
(1) Yamamoto, A., Ashihara, E., Nakagawa, Y. et al. Allograft inflammatory factor-1 is overexpressed and induces fibroblast chemotaxis in the skin of sclerodermatous GVHD in a murine model. Immunol. Lett. 135 (1-2), 144-150 (2011).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
199
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,617 Da
NCBI Official Full Name
allograft inflammatory factor 1 isoform 3
NCBI Official Synonym Full Names
allograft inflammatory factor 1
NCBI Official Symbol
AIF1
NCBI Official Synonym Symbols
IBA1; IRT1; AIF-1; IRT-1
NCBI Protein Information
allograft inflammatory factor 1
UniProt Protein Name
Allograft inflammatory factor 1
Protein Family
UniProt Gene Name
AIF1
UniProt Synonym Gene Names
G1; IBA1; AIF-1

NCBI Description

This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]

Uniprot Description

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Research Articles on AIF1

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Product Notes

The AIF1 aif1 (Catalog #AAA859403) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AIF1 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AIF1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20,000-1:80,000 WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the AIF1 aif1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AIF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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