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Testing Data

Rabbit AIBZIP Polyclonal Antibody | anti-AIBZIP antibody

Anti-AIBZIP - CREB3L4 Antibody

Gene Names
CREB3L4; JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP
Reactivity
Human. Predicted: Mouse, Rat.
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
AIBZIP; Polyclonal Antibody; Anti-AIBZIP - CREB3L4 Antibody; Anti-AIBZIP Antibody; anti-AIBZIP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human. Predicted: Mouse, Rat.
Clonality
Polyclonal
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
395
Applicable Applications for anti-AIBZIP antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:1,000-1:2,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal AIBZIP(1) antibody was raised against a peptide corresponding to the C terminal amino acids of Human AIBZIP. The peptide sequence: PSGRIRSVLHADEM.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Testing Data

Testing Data
References
Qi,H., Fillion,C., Labrie,Y.,,et,al. AIbZIP,a novel bZIP gene located on chromosome 1q21.3 that is highly expressed in prostate tumors and of which the expression is up-regulated by androgens in LNCaP human prostate cancer cells. Cancer Research.2002;62:721-733.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
41,275 Da
NCBI Official Full Name
androgen-induced basic leucine zipper
NCBI Official Synonym Full Names
cAMP responsive element binding protein 3-like 4
NCBI Official Symbol
CREB3L4
NCBI Official Synonym Symbols
JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP
NCBI Protein Information
cyclic AMP-responsive element-binding protein 3-like protein 4; CREB-4; androgen-induced basic leucine zipper protein; attaching to CRE-like 1; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 3-like protein 4; cAMP-responsive element-binding protein 4; cyclic AMP-responsive element-binding protein 4; tisp40; transcript induced in spermiogenesis protein 40
UniProt Protein Name
Cyclic AMP-responsive element-binding protein 3-like protein 4
UniProt Gene Name
CREB3L4
UniProt Entry Name
CR3L4_HUMAN

NCBI Description

This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Uniprot Description

CREB3L4: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements. Belongs to the bZIP family. ATF subfamily.

Protein type: Transcription factor; Endoplasmic reticulum; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane; nucleus

Biological Process: transcription, DNA-dependent; unfolded protein response; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter

Research Articles on AIBZIP

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Product Notes

The AIBZIP creb3l4 (Catalog #AAA416001) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-AIBZIP - CREB3L4 Antibody reacts with Human. Predicted: Mouse, Rat. and may cross-react with other species as described in the data sheet. AAA Biotech's AIBZIP can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:1,000-1:2,000 Immunohistochemistry: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the AIBZIP creb3l4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AIBZIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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