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Western Blot (WB) (AAA1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AAA1 antibody detected the AAA1 protein (arrow).)

Rabbit anti-Human AAA1 Polyclonal Antibody | anti-SLC7A10 antibody

AAA1 Antibody (C-term)

Gene Names
SLC7A10; ASC1; asc-1; HASC-1
Reactivity
Human
Applications
Western Blot, ELISA, Flow Cytometry, Functional Assay
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
AAA1; Polyclonal Antibody; AAA1 Antibody (C-term); Asc-type amino acid transporter 1; Asc-1; Solute carrier family 7 member 10; SLC7A10; ASC1; anti-SLC7A10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This AAA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human AAA1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
495-523
Sequence Length
523
Applicable Applications for anti-SLC7A10 antibody
Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(AAA1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AAA1 antibody detected the AAA1 protein (arrow).)

Western Blot (WB) (AAA1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AAA1 antibody detected the AAA1 protein (arrow).)

Flow Cytometry (FC/FACS)

(AAA1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (AAA1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-SLC7A10 antibody
SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070),
mediates high-affinity transport of D-serine and several other
neutral amino acids (Nakauchi et al., 2000 [PubMed
10863037]).
Product Categories/Family for anti-SLC7A10 antibody
References
Imielinski, M., et al. Nat. Genet. 41(12):1335-1340(2009)
Broer, S. Physiol. Rev. 88(1):249-286(2008)
Xu, D., et al. Mol. Cell Proteomics 4(8):1061-1071(2005)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56798
NCBI Official Full Name
asc-type amino acid transporter 1
NCBI Official Synonym Full Names
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
NCBI Official Symbol
SLC7A10
NCBI Official Synonym Symbols
ASC1; asc-1; HASC-1
NCBI Protein Information
asc-type amino acid transporter 1
UniProt Protein Name
Asc-type amino acid transporter 1
UniProt Gene Name
SLC7A10
UniProt Synonym Gene Names
ASC1; Asc-1
UniProt Entry Name
AAA1_HUMAN

NCBI Description

SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]

Uniprot Description

SLC7A10: Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse. Belongs to the amino acid-polyamine-organocation (APC) superfamily.

Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: L-serine transmembrane transporter activity; neutral amino acid transmembrane transporter activity

Biological Process: D-alanine transport; neutral amino acid transport; amino acid transport; ion transport; blood coagulation; transmembrane transport; D-serine transport; leukocyte migration; L-serine transport

Research Articles on SLC7A10

Similar Products

Product Notes

The SLC7A10 slc7a10 (Catalog #AAA9211271) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 495-523. The AAA1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AAA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the SLC7A10 slc7a10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AAA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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