Rabbit anti-Human AGXT2L2 Polyclonal Antibody | anti-AGXT2L2 antibody

AGXT2L2 Rabbit pAb

Cat. Num. AAA4757879

• Gene Names: PHYKPL; PHLU; AGXT2L2
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity purified
• Synonyms: AGXT2L2; Polyclonal Antibody; AGXT2L2 Rabbit pAb; PHLU; anti-AGXT2L2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: -20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

• Applicable Applications for anti-AGXT2L2 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Fusion protein of human AGXT2L2
• Conjugation: Unconjugated
• Molecular Function: This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants.
• Modification: Unmodified
• Cell Position: Mitochondrion
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human lymphoma tissue, Primary antibody: 821549(AGXT2L2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds)

Product Categories/Family for anti-AGXT2L2 antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 14124965
• NCBI GeneID: 85007
• UniProt Accession #: Q8IUZ5; Q8WYS6; Q96HW8; A8K7P6; B3KN36; D3DWP9
• Molecular Weight: 18,857 Da
• NCBI Official Full Name: Homo sapiens alanine-glyoxylate aminotransferase 2-like 2, mRNA
• NCBI Official Synonym Full Names: 5-phosphohydroxy-L-lysine phospho-lyase
• NCBI Official Symbol: PHYKPL
• NCBI Official Synonym Symbols: PHLU; AGXT2L2
• NCBI Protein Information: 5-phosphohydroxy-L-lysine phospho-lyase
• UniProt Protein Name: 5-phosphohydroxy-L-lysine phospho-lyase
• UniProt Gene Name: AGXT2L2
• UniProt Entry Name: AT2L2_HUMAN

NCBI Description

This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Uniprot Description

AGXT2L2: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 4.2.3.134

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: mitochondrion

Molecular Function: lyase activity; transaminase activity; pyridoxal phosphate binding

Biological Process: metabolic process

Disease: Phosphohydroxylysinuria