Immunohistochemistry (IHC)
Rabbit AGTRAP Polyclonal Antibody | anti-AGTRAP antibody
Anti-AGTRAP Antibody
Gene Names
Agtrap; AT1R; Atrap; D4Wsu124e; 3300002E14Rik
Reactivity
Human. Not yet tested in other species
Applications
ELISA, Immunohistochemistry
Purity
Affinity purified
Synonyms
AGTRAP; Polyclonal Antibody; Anti-AGTRAP Antibody; anti-AGTRAP antibody
Host
Rabbit
Reactivity
Human. Not yet tested in other species
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
161
Applicable Applications for anti-AGTRAP antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA titer: 1:1,000-1:10,000
Immunohistochemistry: 1:50-200
Optimal dilutions/concentrations should be determined by the end user
Immunohistochemistry: 1:50-200
Optimal dilutions/concentrations should be determined by the end user
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal AGTRAP antibody was raised against a peptide near the C terminal residues of human AGTRAP protein.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Related Product Information for anti-AGTRAP antibody
This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
References
(1) Lopez-Ilasaca,M., Liu,X., Tamura,K.et al.The angiotensin II type I receptor-associated protein, ATRAP, is a transmembrane protein and a modulator of angiotensin II signaling.Mol. Biol. Cell 14 (12), 5038-5050 (2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
17,525 Da
NCBI Official Full Name
Agtrap protein
NCBI Official Synonym Full Names
angiotensin II, type I receptor-associated protein
NCBI Official Symbol
Agtrap
NCBI Official Synonym Symbols
AT1R; Atrap; D4Wsu124e; 3300002E14Rik
NCBI Protein Information
type-1 angiotensin II receptor-associated protein; AT1 receptor; AT1 receptor-associated protein; angiotensin II receptor, type I
UniProt Protein Name
Type-1 angiotensin II receptor-associated protein
Protein Family
UniProt Gene Name
Agtrap
UniProt Entry Name
ATRAP_MOUSE
Uniprot Description
AGTRAP: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: nucleoplasm; Golgi apparatus; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; integral to membrane; plasma membrane; cytoplasmic vesicle; cell cortex
Molecular Function: protein binding; angiotensin type II receptor activity
Biological Process: regulation of blood pressure
Research Articles on AGTRAP
Similar Products
Product Notes
The AGTRAP agtrap (Catalog #AAA416215) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-AGTRAP Antibody reacts with Human. Not yet tested in other species and may cross-react with other species as described in the data sheet. AAA Biotech's AGTRAP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Peptide ELISA titer: 1:1,000-1:10,000 Immunohistochemistry: 1:50-200 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the AGTRAP agtrap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AGTRAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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