Typical Testing Data/Standard Curve (for reference only)
Mouse AT1R (angiotensin II receptor type 1) ELISA Kit | AT1R elisa kit
Mouse AT1R (angiotensin II receptor type 1) ELISA Kit
Gene Names
Agtrap; AT1R; Atrap; D4Wsu124e; 3300002E14Rik
Reactivity
Mouse
Synonyms
AT1R (angiotensin II receptor type 1); Mouse AT1R (angiotensin II receptor type 1) ELISA Kit; angiotensin II receptor type 1; AT1R; Type-1 angiotensin II receptor-associated protein; AT1R elisa kit
Reactivity
Mouse
Specificity
This assay has high sensitivity and excellent specificity for detection of AT1R. No significant cross-reactivity or interference between AT1R and analogues was observed.
Samples
Serum, plasma, tissue homogenates and other biological fluids
Assay Type
Quantitative Sandwich
Detection Range
78.125-5000pg/ml
Sensitivity
46.875pg/ml
Intra-assay Precision
CV<8%
Inter-assay Precision
CV<10%
Preparation and Storage
Store at 2-8 degree C for 6 months
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for AT1R elisa kit
Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Capture antibody was pre-coated onto 96-well plates. And the biotin conjugated antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the target amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of target can be calculated.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
17,525 Da
NCBI Official Full Name
Agtrap protein
NCBI Official Synonym Full Names
angiotensin II, type I receptor-associated protein
NCBI Official Symbol
Agtrap
NCBI Official Synonym Symbols
AT1R; Atrap; D4Wsu124e; 3300002E14Rik
NCBI Protein Information
type-1 angiotensin II receptor-associated protein; AT1 receptor; AT1 receptor-associated protein; angiotensin II receptor, type I
UniProt Protein Name
Type-1 angiotensin II receptor-associated protein
UniProt Gene Name
Agtrap
UniProt Synonym Gene Names
Atrap
UniProt Entry Name
ATRAP_MOUSE
Uniprot Description
AGTRAP: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Endoplasmic reticulum; Membrane protein, multi-pass
Cellular Component: nucleoplasm; Golgi apparatus; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; plasma membrane; integral to membrane; cell cortex; cytoplasmic vesicle
Molecular Function: protein binding; angiotensin type II receptor activity
Biological Process: regulation of blood pressure
Research Articles on AT1R
Similar Products
Product Notes
The Mouse AT1R agtrap (Catalog #AAA7612374) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7612374 ELISA Kit recognizes Mouse AT1R. It is sometimes possible for the material contained within the vial of "AT1R (angiotensin II receptor type 1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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