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Rabbit anti-Human ADP-ribosylation factor 4 Polyclonal Antibody | anti-ARF4 antibody
Rabbit anti-human ADP-ribosylation factor 4 polyclonal Antibody, HRP conjugated
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
ARF4: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family.
Protein type: G protein; G protein, monomeric; Motility/polarity/chemotaxis; G protein, monomeric, ARF
Chromosomal Location of Human Ortholog: 3p14.3
Cellular Component: cytosol; dendritic spine; Golgi apparatus; membrane
Molecular Function: epidermal growth factor receptor binding; GTP binding; GTPase activity; protein binding
Biological Process: apical protein localization; brain development; cell migration; cellular protein metabolic process; epidermal growth factor receptor signaling pathway; ER to Golgi vesicle-mediated transport; establishment and/or maintenance of epithelial cell polarity; learning; negative regulation of apoptosis; organelle organization and biogenesis; phospholipase D activation; positive regulation of transcription from RNA polymerase II promoter; post-translational protein modification; protein amino acid ADP-ribosylation; protein amino acid N-linked glycosylation via asparagine; protein transport; response to axon injury; small GTPase mediated signal transduction
Research Articles on ARF4
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Product Notes
The ARF4 arf4 (Catalog #AAA715033) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human ADP-ribosylation factor 4 polyclonal Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ADP-ribosylation factor 4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the ARF4 arf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADP-ribosylation factor 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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