Rabbit anti-Human ADAT3 Polyclonal Antibody | anti-ADAT3 antibody

ADAT3, NT (ADAT3, tRNA-specific adenosine deaminase-like protein 3, tRNA-specific adenosine-34 deaminase subunit ADAT3) (FITC)

Cat. Num. AAA6271621

• Gene Names: ADAT3; TAD3; MRT36; FWP005; MST121; S863-5; MSTP121
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ADAT3; Polyclonal Antibody; NT (ADAT3; tRNA-specific adenosine deaminase-like protein 3; tRNA-specific adenosine-34 deaminase subunit ADAT3) (FITC); tRNA-specific adenosine-34 deaminase subunit ADAT3; anti-ADAT3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
• Sequence Length: 351

• Applicable Applications for anti-ADAT3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ADAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the N-terminal region of human ADAT3.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ADAT3 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the ADAT3 antibody detected the ADAT3 protein (arrow).)

Related Product Information for anti-ADAT3 antibody

ADAT3 may be involved in deamination of adenosine-34 to inosine in many tRNAs as a regulatory subunit (Potential).

Product Categories/Family for anti-ADAT3 antibody

Antibodies; Enzymes

References

Matsuoka, S., et al. Science 316(5828):1160-1166(2007). Schaub, M., et al. Biochimie 84(8):791-803(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 19923945
• NCBI GeneID: 113179
• NCBI Accession #: NP_612431.1
• NCBI GenBank Nucleotide #: NP_612431.1
• UniProt Accession #: Q96EY9
• NCBI Official Full Name: tRNA-specific adenosine deaminase-like protein 3
• NCBI Official Synonym Full Names: adenosine deaminase tRNA specific 3
• NCBI Official Symbol: ADAT3
• NCBI Official Synonym Symbols: TAD3; MRT36; FWP005; MST121; S863-5; MSTP121
• NCBI Protein Information: probable inactive tRNA-specific adenosine deaminase-like protein 3
• UniProt Protein Name: Probable inactive tRNA-specific adenosine deaminase-like protein 3
• Protein Family: Probable inactive tRNA-specific adenosine deaminase-like protein
• UniProt Gene Name: ADAT3
• UniProt Synonym Gene Names: TAD3
• UniProt Entry Name: ADAT3_HUMAN

NCBI Description

This gene encodes a subunit of a tRNA-specific adenosine deaminase. This heterodimeric enzyme converts adenosine to inosine in the tRNA anticodon. A mutation in this gene causes a syndrome characterized by intellectual disability and strabismus. This gene shares its 5' exon with the overlapping gene, secretory carrier membrane protein 4 (Gene ID: 113178). [provided by RefSeq, Jul 2016]