Rabbit anti-Human ADAM7 Polyclonal Antibody | anti-ADAM7 antibody

ADAM7 Antibody

Cat. Num. AAA7004575

• Gene Names: ADAM7; EAPI; GP83; GP-83; ADAM 7; ADAM-7
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: >95%,Protein G purified
• Synonyms: ADAM7; Polyclonal Antibody; ADAM7 Antibody; Disintegrin and metalloproteinase domain-containing protein 7; ADAM 7; Sperm maturation-related glycoprotein GP-83; GP83; anti-ADAM7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 754

• Applicable Applications for anti-ADAM7 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Immunogen: Recombinant human Disintegrin and metalloproteinase domain-containing protein 7 protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-25142
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue MBS7004575 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human melanoma MBS7004575 at dilution 1:100)

Related Product Information for anti-ADAM7 antibody

May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein.

NCBI and Uniprot Product Information

• NCBI GI #: 114326453
• NCBI GeneID: 8756
• NCBI Accession #: NP_003808.2
• NCBI GenBank Nucleotide #: NM_003817.3
• UniProt Accession #: Q9H2U9; O75959; Q6PEJ6; A8K8X7
• Molecular Weight: 24,414 Da
• NCBI Official Full Name: disintegrin and metalloproteinase domain-containing protein 7 preproprotein
• NCBI Official Synonym Full Names: ADAM metallopeptidase domain 7
• NCBI Official Symbol: ADAM7
• NCBI Official Synonym Symbols: EAPI; GP83; GP-83; ADAM 7; ADAM-7
• NCBI Protein Information: disintegrin and metalloproteinase domain-containing protein 7
• UniProt Protein Name: Disintegrin and metalloproteinase domain-containing protein 7
• Protein Family: Disintegrin and metalloproteinase domain-containing protein
• UniProt Gene Name: ADAM7
• UniProt Synonym Gene Names: GP83; ADAM 7
• UniProt Entry Name: ADAM7_HUMAN

NCBI Description

This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. [provided by RefSeq, Oct 2011]

Uniprot Description

ADAM7: May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. Has been found to be frequently mutated in melanoma. ADAM7 mutations may play a role in melanoma progression and metastasis.

Protein type: Protease; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p21.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: metalloendopeptidase activity; zinc ion binding

Biological Process: proteolysis