Rabbit anti-Human ADAM5 Polyclonal Antibody | anti-ADAM5 antibody

ADAM5 Rabbit Polyclonal

Cat. Num. AAA766375

• Gene Names: Adam5; tMDCII; tMDC II
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: ADAM5; Polyclonal Antibody; ADAM5 Rabbit Polyclonal; anti-ADAM5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 699

• Applicable Applications for anti-ADAM5 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Immunogen: ADAM metallopeptidase domain 5 pseudogene
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis using MBS766375 (ADAM5P antibody) at dilution of 1:50)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS766375 (ADAM5P antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 62740133
• NCBI GeneID: 11499
• Molecular Weight: 78,557 Da
• NCBI Official Full Name: Adam5 protein
• NCBI Official Synonym Full Names: a disintegrin and metallopeptidase domain 5
• NCBI Official Symbol: Adam5
• NCBI Official Synonym Symbols: tMDCII; tMDC II
• NCBI Protein Information: disintegrin and metalloproteinase domain-containing protein 5
• UniProt Protein Name: Disintegrin and metalloproteinase domain-containing protein 5
• Protein Family: Disintegrin and metalloproteinase domain-containing protein
• UniProt Gene Name: Adam5
• UniProt Synonym Gene Names: Tmdc2; tMDC II
• UniProt Entry Name: ADAM5_MOUSE

NCBI Description

This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. This gene is located in a cluster of related ADAM genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. [provided by RefSeq, May 2016]

Uniprot Description

ADAM5P: This is a non catalytic metalloprotease-like protein. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease

Cellular Component: integral to membrane; membrane

Molecular Function: metalloendopeptidase activity; metallopeptidase activity; zinc ion binding

Biological Process: proteolysis